5 Results for "

return

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "return" in MCE Product Catalog:

9
Dimethyl malonate
Dimethyl malonate
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9 Cited Publications
Referencia número: HY-Y1787
No. CAS: 108-59-8
Category:  

Natural Products Melia azedarach L. Plants Meliaceae

Target:  

Apoptosis

Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .
1
BBO-8520
BBO-8520
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1 Cited Publications
Referencia número: HY-158107
No. CAS: 2893809-51-1
Pureza:  98.90%
Target:  

Ras

Áreas de investigación:  

Cancer

BBO-8520 is a direct small molecule covalent inhibitor targeting KRAS G12C with high oral availability. BBO-8520 has the characteristics of KRAS G12C (OFF) inhibitor and the function of blocking KRAS G12C (ON) signal. BBO-8520 inhibits cell proliferation by inhibiting KRAS G12C (ON) by binding GTP protein. BBO-8520 can block RAS-RAF1 interaction and return KRAS G12C to the inactive (OFF) state. BBO-8520 can be used for the research of cancer .
Dimethyl malonate (Standard)
Dimethyl malonate (Standard)
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Referencia número: HY-Y1787R
No. CAS: 108-59-8
Category:  

Natural Products Melia azedarach L. Plants Meliaceae

Target:  

Reference Standards Apoptosis

Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .
FPL 66564
FPL 66564
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Referencia número: HY-182445
No. CAS: 140369-78-4
Target:  

Angiotensin-converting Enzyme (ACE)

Áreas de investigación:  

Cardiovascular Disease

FPL 66564 is a short-acting angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 5.7 nM against rabbit ACE. FPL 66564 inhibits ACE activity at the functional level and is hydrolyzed in human blood into inactive hydrophilic metabolites. FPL 66564 modulates angiotensin I-induced pressor responses in anesthetized rats, and its effects rapidly return to baseline after cessation of intravenous infusion. FPL 66564 can be used for research on cardiovascular regulation related to critical illness .
(4R)-BBO-8520
(4R)-BBO-8520
0 Images
Referencia número: HY-158107A
No. CAS: 2893809-52-2
Target:  

Drug Isomer Ras

Áreas de investigación:  

Cancer

(4R)-BBO-8520 (Compound 314), an isomer of BBO-8520 (HY-158107), is a selective KRAS G12C inhibitor. BBO-8520 has the characteristics of KRAS G12C (OFF) inhibitor and the function of blocking KRAS G12C (ON) signal. BBO-8520 inhibits cell proliferation by inhibiting KRAS G12C (ON) by binding GTP protein. BBO-8520 can block RAS-RAF1 interaction and return KRAS G12C to the inactive (OFF) state. (4R)-BBO-8520 can be used for the research of cancer .
Assay Types