SLC17A9 - solute carrier family 17 member 9 Gene

Also Known as VNUT; POROK8; C20orf59

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 63910

About SLC17A9

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:62,952,709-62,969,585 (from NCBI)

This gene has 7 transcripts (splice variants), 259 orthologues, 12 paralogues and is associated with 2 phenotypes. Broad expression in stomach (RPKM 12.3), bone marrow (RPKM 8.3) and 20 other tissues.

Summary

This gene encodes a member of a family of transmembrane proteins that are involved in the transport of small molecules. The encoded protein participates in the vesicular uptake, storage, and secretion of adenoside triphosphate (ATP) and Other nucleotides. A mutation in this gene was found in individuals with autosomal dominant disseminated superficial actinic porokeratosis-8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

SLC17A9 Products (2)

mRNA	Protein	Name
NM_001302643.2	NP_001289572.2	solute carrier family 17 member 9 isoform 2
NM_022082.4	NP_071365.4	solute carrier family 17 member 9 isoform 1

SLC17A9 Protein Structure

MFS_1

0
100
200
300
400
436 a.a.

Protein Preferred Names	Protein Names
solute carrier family 17 member 9	solute carrier family 17 (vesicular nucleotide transporter), member 9

SLC17A9 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	SLC17A9	Q9BYT1	SMG9	Homo sapiens	Q9H0W8	Validated Y2H	32296183
Intra	SLC17A9	Q9BYT1	DIABLO	Homo sapiens	Q9NR28	Validated Y2H	32296183
Intra	SLC17A9	Q9BYT1	MYG1	Homo sapiens	Q9HB07	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Porokeratosis 8, Disseminated Superficial Actinic Type	POROK8 Porokeratosis, Type 8, Disseminated Superficial Actinic Type
Porokeratosis	Disseminated Superficial Actinic Porokeratosis Dsap Porokeratosis Of Mibelli Porokeratosis, Disseminated Superficial Actinic Porokeratosis, Disseminated Superficial Actinic, 1
Punctate Porokeratosis	Porokeratosis, Punctate Keratoderma, Palmoplantar, Punctate Type Ii
Linear Porokeratosis	Congenital Facial Linear Porokeratosis Porokeratosis, Linear
Deafness, Autosomal Dominant 67	DFNA67 Autosomal Dominant Nonsyndromic Deafness 67 Autosomal Dominant Deafness 67 Deafness, Autosomal Dominant, 67 Deafness, Autosomal Dominant, Type 67
Atrophoderma Vermiculata	Atrophoderma Vermiculatum Folliculitis Ulerythematosa Reticulata Atrophodermia Vermiculata Honeycomb Atrophy Atrophodermia Reticulata Symmetrica Faciei AVA Atrophodermia Reticulata Folliculitis Ulerythematosa Folliculitis Ulerythematosa Reticulate Burnett Schwartz Berberian Syndrome
Thiamine-Responsive Megaloblastic Anemia Syndrome	TRMA Rogers Syndrome Thiamine-Responsive Myelodysplasia Thiamine-Responsive Anemia Syndrome Thiamine Metabolism Dysfunction Syndrome 1 Thmd1 Megaloblastic Anemia, Thiamine-Responsive, With Diabetes Mellitus And Sensorineural Deafness Thiamine-Responsive Megaloblastic Anemia With Diabetes Mellitus And Sensorineural Deafness Thiamine Responsive Megaloblastic Anemia Syndrome Megaloblastic Anemia Thiamine-Responsive With Diabetes Mellitus And Sensorineural Deafness Thiamine-Responsive Megaloblastic Anemia Thiamine-Responsive Anaemia Syndrome Thiamine-Responsive Megaloblastic Anaemia Syndrome Thiamine-Responsive Megaloblastic Anaemia With Diabetes Mellitus And Sensorineural Deafness Thiamine-Responsive Megaloblastic Anemia With Diabetes Mellitus And Sensorineural Hearing Loss

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13042	SLC17A9 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SLC17A9	VGNC	VGNC:65225
Mus musculus	SLC17A9	MGD	MGI:1919107
Rattus norvegicus	SLC17A9	RGD	RGD:1311940
Bos taurus	SLC17A9	VGNC	VGNC:34704
Macaca mulatta	SLC17A9	VGNC	VGNC:77492
Canis familiaris	SLC17A9	VGNC	VGNC:46254
Others	SLC17A9	NCBI