MEIS-IN-2
Based on 1 Customer Validation
MEIS-IN-2 is a myeloid ecotropic viral integration site 1 (MEIS1) inhibitor.
For research use only. We do not sell to patients.
- Purity: 99.33%
- CAS No.: 2761326-86-5
- Formula: C23H21ClN2O4
- Molecular Weight:424.88
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2761326-86-5
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Appearance Solid
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Molecular Weight 424.88
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Formula C23H21ClN2O4
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Color White to off-white
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SMILES
O=C(NC1=CC=CC(Cl)=C1)C2=CC=C(OCC(NCC3=CC=C(OC)C=C3)=O)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (294.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3536 mL | 11.7680 mL | 23.5361 mL | 58.8401 mL |
| 5 mM | 0.4707 mL | 2.3536 mL | 4.7072 mL | 11.7680 mL | |
| 10 mM | 0.2354 mL | 1.1768 mL | 2.3536 mL | 5.8840 mL | |
| 15 mM | 0.1569 mL | 0.7845 mL | 1.5691 mL | 3.9227 mL | |
| 20 mM | 0.1177 mL | 0.5884 mL | 1.1768 mL | 2.9420 mL | |
| 25 mM | 0.0941 mL | 0.4707 mL | 0.9414 mL | 2.3536 mL | |
| 30 mM | 0.0785 mL | 0.3923 mL | 0.7845 mL | 1.9613 mL | |
| 40 mM | 0.0588 mL | 0.2942 mL | 0.5884 mL | 1.4710 mL | |
| 50 mM | 0.0471 mL | 0.2354 mL | 0.4707 mL | 1.1768 mL | |
| 60 mM | 0.0392 mL | 0.1961 mL | 0.3923 mL | 0.9807 mL | |
| 80 mM | 0.0294 mL | 0.1471 mL | 0.2942 mL | 0.7355 mL | |
| 100 mM | 0.0235 mL | 0.1177 mL | 0.2354 mL | 0.5884 mL |
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