Labetalol hydrochloride (Standard)
Based on 1 Customer Validation
Labetalol hydrochloride (Standard) is the analytical standard of Labetalol hydrochloride (HY-B1108). This product is intended for research and analytical applications. Labetalol (AH5158) hydrochloride is an orally available, selective α1-adrenergic recepto and non-selective β-adrenergic receptor competitive antagonist. Labetalol hydrochloride is an antihypertensive molecule that partially crosses the blood-brain barrier and has little effect on cardiac output. Labetalol hydrochloride can be used in the study of cardiovascular diseases, such as hypertension during pregnancy.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 32780-64-6
- Formula: C19H25ClN2O3
- Molecular Weight:364.87
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 32780-64-6
-
Appearance Solid
-
Molecular Weight 364.87
-
Formula C19H25ClN2O3
-
Color White to off-white
-
SMILES
O=C(N)C1=CC(C(O)CNC(C)CCC2=CC=CC=C2)=CC=C1O.[H]Cl
-
Synonyms
AH-5158 hydrochloride(Standard); Sch-15719W (Standard)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
-
SDS (704 KB)
- English - EN (704 KB)
- Français - FR (704 KB)
- Deutsch - DE (704 KB)
- Norwegian - NO (704 KB)
- Español - ES (704 KB)
- Swedish - SV (704 KB)
- Italian - IT (704 KB)
- Portuguese - PT (704 KB)
-
Handling Instructions (2659 KB)
References
[1]. Greenslade FC, et al. Labetalol binding to specific alpha- and beta-adrenergic sites in vitro and its antagonism of adrenergic responses in vivo. J Mol Cell Cardiol. 1979 Aug;11(8):803-11. [Content Brief]
[2]. Erdtsieck-Ernste EB, et al. Changes in adrenoceptors and monoamine metabolism in neonatal and adult rat brain after postnatal exposure to the antihypertensive labetalol. Br J Pharmacol. 1992 Jan;105(1):37-44. [Content Brief]
[3]. Johnson JD, et al. Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines. Neuroscience. 2005;135(4):1295-307. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)