PD1-PDL1-IN 1
PD1-PDL1-IN 1 (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator.
For research use only. We do not sell to patients.
- CAS No.: 2005454-12-4
- Formula: C14H23N7O6
- Molecular Weight:385.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is a receptor of the CD28 superfamily that negatively regulates T cell antigen receptor signalling by interacting with the specific ligands. PD-1 is suggested to play significant role in the maintenance of self-tolerance[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2005454-12-4
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Molecular Weight 385.38
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Formula C14H23N7O6
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SMILES
C[C@@H](O)[C@@H](C(O)=O)NC(N[C@H](C1=NC(N2CCNCC2)=NO1)CC(N)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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