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Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s)

(Synonyms: CMC-Na (Viscosity:5000-15000 mPa.s))

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Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

For research use only. We do not sell to patients.

Purity: 97.0%
CAS No.: 9004-32-4

Storage:

Powder -20°C, 3 years , 4°C, 2 years

Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s) Chemical Structure

CAS No.: 9004-32-4

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Biological Activity
- Description
- In Vivo
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

In Vivo

Protocal for preparing 0.5% CMC-Na Solution
Measure 0.5g of dry CMC-Na and dissolved in 100 ml ddH2O/0.9% Saline (0.9 g NaCl in 100 ml ddH2O) to make a clear solution.
Under the condition of stirring and heating (50-65°C), adding CMC-Na slowly to ddH2O/0.9% Saline helps to accelerate dissolution.

Note
1.You must ensure that your CMC-Na solution does not exist solid-liquid separation phenomenon. The solution is in a uniform and transparent state has no particles in it.
2.Completely dissolution of CMC-Na may requires 4 hours or more longer.

In a pharmacological test, CMC-Na (oral;5% in water; 1 year) is well tolerated in rats^[2].
In an acute oral toxicity study in female mice, LD₅₀ of CMC-Na for female mice is 14 g/kg body weight of mice, equivalent to 9.8 g/kg body weight of rat, categorized as practically non-toxic according to Loomis criteria (LD₅₀ 5-15g/kg body weight of rat)^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 9004-32-4
Appearance Solid
Color White to off-white
SMILES

[Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s)]
Synonyms

CMC-Na (Viscosity:5000-15000 mPa.s)
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years

Solvent & Solubility

In Vitro:

H₂O : 6.25 mg/mL (Need ultrasonic)

View the Complete Stock Solution Preparation Table

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage
mg/kg
Animal Weight (Per Animal)
g
Dosing Volume (Per Animal)
μL
Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Working solution concentration: 0.22 mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact

MedChemExpress (MCE) .

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Du XH, et al. Dexamethasone and sodium carboxymethyl cellulose prevent postoperative intraperitoneal adhesions in rats. Braz J Med Biol Res. 2015 Apr;48(4):344-8. [Content Brief]

[2]. Common Vehicles for Nonclinical Evaluation of Therapeutic Agents.

[3]. Ida Musfiroh, et al. Toxicity Evaluation of Na-CMC synthesized from Cellulose of Water Hyacinth (Eichhornia crassipes (Mart.) Solms).ISSN: 0975-8585

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s)

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Biological Activity
- Description
- In Vivo
Chemical Information
Solvent & Solubility
- In Vitro
- In Vivo Dissolution Calculator
Purity & Documentation
References

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Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s)

Biological Activity

Chemical Information

Solvent & Solubility

Purity & Documentation

References

Calculators

Help & FAQs

Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s) Related Classifications

Cat. No.: HY-Y1889