C5a Receptor agonist, W5Cha
Based on 1 Customer Validation
C5a Receptor agonist, W5Cha (Peptide 1) is a selective complement C5a receptor (C5aR) agonist (EC50=0.2 μM), a hexapeptide derived from the C-terminus of C5a with specific amino acid modifications. C5a Receptor agonist, W5Cha is able to interact with the Arg-206 site of the C5a receptor through its C-terminal arginine, thereby activating the receptor.
For research use only. We do not sell to patients.
- Purity: 99.13%
- CAS No.: 144555-23-7
- Formula: C45H74N10O7
- Molecular Weight:867.13
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 144555-23-7
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Appearance Solid
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Molecular Weight 867.13
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Formula C45H74N10O7
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Color White to off-white
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Sequence
{N-me-Phe}-Lys-Pro-{d-Cha}-{Cha}-{d-Arg}
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Sequence Shortening
{N-me-Phe}-KP-{d-Cha}-{Cha}-{d-Arg}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (115.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1532 mL | 5.7661 mL | 11.5323 mL | 28.8307 mL |
| 5 mM | 0.2306 mL | 1.1532 mL | 2.3065 mL | 5.7661 mL | |
| 10 mM | 0.1153 mL | 0.5766 mL | 1.1532 mL | 2.8831 mL | |
| 15 mM | 0.0769 mL | 0.3844 mL | 0.7688 mL | 1.9220 mL | |
| 20 mM | 0.0577 mL | 0.2883 mL | 0.5766 mL | 1.4415 mL | |
| 25 mM | 0.0461 mL | 0.2306 mL | 0.4613 mL | 1.1532 mL | |
| 30 mM | 0.0384 mL | 0.1922 mL | 0.3844 mL | 0.9610 mL | |
| 40 mM | 0.0288 mL | 0.1442 mL | 0.2883 mL | 0.7208 mL | |
| 50 mM | 0.0231 mL | 0.1153 mL | 0.2306 mL | 0.5766 mL | |
| 60 mM | 0.0192 mL | 0.0961 mL | 0.1922 mL | 0.4805 mL | |
| 80 mM | 0.0144 mL | 0.0721 mL | 0.1442 mL | 0.3604 mL | |
| 100 mM | 0.0115 mL | 0.0577 mL | 0.1153 mL | 0.2883 mL |
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