144555-23-7
Chemical Structure
C5a Receptor agonist, W5Cha
- CAS No.: 144555-23-7
- Formula:C45H74N10O7
- Molecular Weight:867.13
InChIKey: OLWJKQKSDDUCKB-PHDGMBCWSA-N
SMILES: N=C(N)NCCC[C@H](C(O)=O)NC([C@H](CC1CCCCC1)NC([C@@H](CC2CCCCC2)NC([C@H]3N(CCC3)C([C@H](CCCCN)NC([C@@H](NC)CC4=CC=CC=C4)=O)=O)=O)=O)=O
Biological Activity: C5a Receptor agonist, W5Cha (Peptide 1) is a selective complement C5a receptor (C5aR) agonist (EC50=0.2 μM), a hexapeptide derived from the C-terminus of C5a with specific amino acid modifications. C5a Receptor agonist, W5Cha is able to interact with the Arg-206 site of the C5a receptor through its C-terminal arginine, thereby activating the receptor[1].
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C5a Receptor agonist, W5Cha | 99.13% | C5a Receptor agonist, W5Cha (Peptide 1) is a selective complement C5a receptor (C5aR) agonist (EC50=0.2 μM), a hexapeptide derived from the C-terminus of C5a with specific amino acid modifications. C5a Receptor agonist, W5Cha is able to interact with the Arg-206 site of the C5a receptor through its C-terminal arginine, thereby activating the receptor. | ||||||||||||||||||||
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Keywords