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Cat. No.: HY-184361

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Juniperonic acid ethyl ester

(Synonyms: Ethyl 20:4BSO)

Juniperonic acid ethyl ester (Ethyl 20:4BSO) is an orally active non-methylene-interrupted ω-3 polyunsaturated fatty acid ethyl ester. Juniperonic acid ethyl ester exists in Platycladus orientalis seed oil. Juniperonic acid ethyl ester reduces the ratio of 20:3n-9 to arachidonic acid in hepatic phosphatidylcholine of rats with essential fatty acid deficiency. Juniperonic acid ethyl ester is applicable to the research of hypertension and hepatic reperfusion injury.

For research use only. We do not sell to patients.

CAS No.: 143202-57-7
Formula: C₂₂H₃₆O₂
Molecular Weight:332.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Juniperonic acid ethyl ester Chemical Structure

CAS No.: 143202-57-7

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Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
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Bioz

Biological Activity

Description

In Vivo

Juniperonic acid ethyl ester (100 mg/day; p.o.; daily; 10 days) reduces the 20:3n-9/AA ratio in liver PC of essential fatty acid-deficient rats to 1.8, demonstrating essential fatty acid activity comparable to that of α-linolenic acid and γ-linolenic acid^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Sprague-Dawley (male, 3-wk-old at study start, essential fatty acid deficiency induced via 66 days of fat-free diet)^[1]
Dosage:

100 mg/day
Administration:

p.o.; daily; 3 days, 10 days
Result:

Reduced the ratio of 20:3n-9 to arachidonic acid (AA) in liver phosphatidylcholine (PC) to 1.8 after 10 days of administration.
Achieved a proportion of AA in liver PC of 6.7% after 10 days of administration.
Achieved a proportion of 20:3n-9 in liver PC of 12.0% after 10 days of administration.

Chemical Information

CAS No. 143202-57-7
Molecular Weight 332.53
Formula C₂₂H₃₆O₂
SMILES

C(=C\CCCC/C=C\C/C=C\C/C=C\CC)\CCCC(OCC)=O
Synonyms

Ethyl 20:4BSO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ikeda I, et al. 5c,11c,14c-eicosatrienoic acid and 5c,11c,14c,17c-eicosatetraenoic acid of Biota orientalis seed oil affect lipid metabolism in the rat. Lipids. 1992 Jul;27(7):500-4. [Content Brief]

[2]. Montañés F, et al. Isolation of non-methylene interrupted or acetylenic fatty acids from seed oils using semi-preparative supercritical chromatography[J]. Journal of the American Oil Chemists' Society, 2017, 94(7): 981-991.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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