Araguspongin B
Xestospongins and araguspongins are marine natural products first isolated from Pacific basin sponges, and noted to have vasodilatory properties.1 Inositol phosphates (IP) are important signal transduction messengers acting via IP3 receptors to promote the mobilization of Ca2+ from intracellular stores.2 Araguspongin B antagonizes the calcium-releasing action of inositol 1,4,5-trisphosphate at the receptor level in cerebral microsomes, with an IC50 of 0.6 μM. It is nearly as potent as xestospongin C as an antagonist of the IP3 receptor.
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- CAS 番号: 123000-02-2
- 分子式: C29H52N2O
- 分子量:444.74
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
化学情報
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CAS 番号 123000-02-2
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分子量 444.74
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分子式 C29H52N2O
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SMILES
[H][C@@]1(CCC2)[C@]3([H])N2CC[C@@](CCCCCC[C@@]4([H])[C@@]5([H])O[C@@](CCN5CCC4)([H])CCCCCC1)([H])C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)