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Camrelizumab

(別名: SHR-1210; INCSHR1210)
4 Cited Publications
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Based on 4 publication(s) in Google Scholar

Camrelizumab (SHR-1210) is a potent humanied high-affinity IgG4-κ monoclonal antibody (mAb) to PD-1. Camrelizumab binds PD-1 at a high affinity of 3 nM and inhibits the binding interaction of PD-1 and PD-L1 with an IC50 of 0.70 nM. Camrelizumab acts as anti-PD-1/PD-L1 agent and can be used for cancer research, including NSCLC, ESCC, Hodgkin lymphoma, and advanced HCC et,al.

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  • 純度: 98.80%
  • CAS 番号: 1798286-48-2
  • 分子量:143.69 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Camrelizumab
  • Experimental Validation Results for Camrelizumab
  • Camrelizumab Chemical Structure
    Camrelizumab 構造式
CAS 番号: 1798286-48-2
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Flow cytometry analysis of PD-1 overexpression Jurkat cells labelling PD-1 with Camrelizumab at 20 nM (Red). Goat anti human IgG Fc (Alexa Fluor488) was used as the secondary antibody at 1/1000 dilution. Isotype control - human IgG (Blue). Unlabeled control - Unlabelled cells (Gray).

  • Camrelizumab Chemical Structure
    1/16
  • Camrelizumab
  • Flow cytometry analysis of PD-1 overexpression Jurkat cells labelling PD-1 with Camrelizumab at 20 nM (Red). Goat anti human IgG Fc (Alexa Fluor488) was used as the secondary antibody at 1/1000 dilution. Isotype control - human IgG (Blue). Unlabeled control - Unlabelled cells (Gray).