Decaethylene glycol dodecyl ether
Based on 1 Customer Validation
Decaethylene glycol dodecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.91%
- CAS 番号: 618113-48-7
- 分子式: C32H66O11
- 分子量:626.86
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保管条件:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MOLT-4 | IC50 |
26 μM
Compound: HL-10
|
Growth inhibition of HIV1 3B infected human MOLT4 cells after 5 days by MTT assay
Growth inhibition of HIV1 3B infected human MOLT4 cells after 5 days by MTT assay
|
[PMID: 18672367] |
| MOLT-4 | IC50 |
41 μM
Compound: HL-10
|
Growth inhibition of human MOLT4 cells after 5 days by MTT assay
Growth inhibition of human MOLT4 cells after 5 days by MTT assay
|
[PMID: 18672367] |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 618113-48-7
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性状 Oil
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分子量 626.86
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分子式 C32H66O11
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Color White to off-white
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SMILES
CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
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別名
PEG10-dodecyl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
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データシート (263 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
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