DOTAM-NHS-ester
DOTAM-NHS-ester is a bifunctional chelator and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-NHS-ester combines the efficient metal chelating ability of DOTAM macrocyclic ligands with the bioconjugation function of NHS ester active groups, and can be widely used in the biomedical field for metal labeling, molecular imaging and drug delivery development.
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- CAS 番号: 2236057-47-7
- 分子式: C20H34N8O7
- 分子量:498.53
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Radionuclide-Drug Conjugates (RDCs) アイソフォーム固有の製品をすべて表示
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生物活性
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RDC Bifunctional Chelator |
DOTAM-NHS ester (composed of DOTAM and NHS ester) is a chelator that forms stable complexes with various metal ions and reacts with amino groups to form stable amide bonds; it is used as a biomolecule labeling reagent to introduce DOTAM into biomolecules for localization and tracking, applied to prepare metal ion-labeled probes for bioimaging, and serves as a contrast agent to improve imaging contrast and resolution by binding to specific biomolecules[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2236057-47-7
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性状 Solid
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分子量 498.53
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分子式 C20H34N8O7
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Color White to off-white
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SMILES
O=C(ON1C(CCC1=O)=O)CN2CCN(CC(N)=O)CCN(CC(N)=O)CCN(CC(N)=O)CC2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (252 KB)
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- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
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