Polyoxyl 40 stearate
Based on 1 Customer Validation
Polyoxyl 40 stearate (PEG 40 stearate) is a nonionic surfactant formed by the esterification of stearic acid with polyethylene glycol (PEG) containing approximately 40 ethoxy units, it is widely used in pharmaceutical preparations, nanodrug carriers, emulsification systems and biomedical materials. Polyoxyl 40 stearate can serve as a matrix component of solid lipid nanoparticles to achieve controlled release of encapsulated antifungal drugs; it can also act as a base material for solid lipid nanoparticles for vaginal administration, and polymerizable groups can be introduced via modification with acryloyl chloride.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 171286-89-8
- 分子式: C98H196O42
- 分子量:2046.58
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Polyoxyl 40 stearate can serve as a matrix component of solid lipid nanoparticles to achieve controlled release of encapsulated antifungal agents; it can also act as a base material for solid lipid nanoparticles for vaginal administration, and polymerizable groups can be introduced via modification with acryloyl chloride[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 171286-89-8
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性状 Solid
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分子量 2046.58
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分子式 C98H196O42
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Color White to off-white
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SMILES
O=C(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)CCCCCCCCCCCCCCCCC
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別名
PEG 40 stearate
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 175 mg/mL (85.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Portuguese - PT (254 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Owen J, et al. The Role of PEG-40-stearate in the Production, Morphology, and Stability of Microbubbles. Langmuir. 2019 Aug 6;35(31):10014-10024. [Content Brief]
[2]. Cassano R, et al. Preparation, characterization and in vitro activities evaluation of solid lipid nanoparticles based on PEG-40 stearate for antifungal drugs vaginal delivery. Drug Deliv. 2016;23(3):1047-56. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.4886 mL | 2.4431 mL | 4.8862 mL | 12.2155 mL |
| 5 mM | 0.0977 mL | 0.4886 mL | 0.9772 mL | 2.4431 mL | |
| 10 mM | 0.0489 mL | 0.2443 mL | 0.4886 mL | 1.2216 mL | |
| 15 mM | 0.0326 mL | 0.1629 mL | 0.3257 mL | 0.8144 mL | |
| 20 mM | 0.0244 mL | 0.1222 mL | 0.2443 mL | 0.6108 mL | |
| 25 mM | 0.0195 mL | 0.0977 mL | 0.1954 mL | 0.4886 mL | |
| 30 mM | 0.0163 mL | 0.0814 mL | 0.1629 mL | 0.4072 mL | |
| 40 mM | 0.0122 mL | 0.0611 mL | 0.1222 mL | 0.3054 mL | |
| 50 mM | 0.0098 mL | 0.0489 mL | 0.0977 mL | 0.2443 mL | |
| 60 mM | 0.0081 mL | 0.0407 mL | 0.0814 mL | 0.2036 mL | |
| 80 mM | 0.0061 mL | 0.0305 mL | 0.0611 mL | 0.1527 mL |
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