Sorbitol dehydrogenase
Based on 1 Customer Validation
Sorbitol dehydrogenase (L-Iditol dehydrogenase) is an oxidoreductasea and catalyses the conversion of sorbitol to fructose with NAD+ as the coenzyme. Sorbitol dehydrogenase catalyses pH-dependent redox reactions between NAD+/NADH and sorbitol/fructose. Sorbitol dehydrogenase is implicated in diabetic complications and is a biomarker of drug-induced liver injury. Sorbitol dehydrogenase can be used for the research of diabetes and liver injury.
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- CAS 番号: 9028-21-1
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Sorbitol dehydrogenase exhibits substrate inhibition at sorbitol concentrations >30 mM and fructose concentrations >100 mM at pH 7.4, with dissociation of the enzyme-coenzyme binary complex as the rate-limiting reaction step[1].
Sorbitol dehydrogenase exhibits higher apparent affinity for fructose and NADH than for sorbitol and NAD+[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 9028-21-1
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性状 Solid
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Color White to off-white
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SMILES
[Sorbitol dehydrogenase]
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別名
L-Iditol dehydrogenase; Polyol dehydrogenase; SDH
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (265 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
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