Z971169476
Z971169476 is a sulfonamide-based protein-RNA interaction inhibitor targeting the KH34 region of insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2/IMP2).
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- CAS 番号: 1356662-88-8
- 分子式: C18H19Cl2NO6S
- 分子量:448.32
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Z971169476 (compound 18) exhibits high kinetic solubility (>200 μM in 1% DMSO/PBS), moderate lipophilicity (LogD7.4 1.68), metabolic instability in mouse and human liver microsomes, high stability in mouse and human plasma, >99% plasma protein binding in mouse and human plasma, and very low Caco-2 cell permeability (Papp 0.40×10-6 cm/s)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1356662-88-8
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分子量 448.32
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分子式 C18H19Cl2NO6S
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SMILES
ClC1=C(OCC(C)C)C=CC(NS(=O)(C2=CC(Cl)=C(OCC(O)=O)C=C2)=O)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)