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Cat. No.: HY-184540

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ALK ligand-2

ALK ligand-2 (compound 3) is a ALK ligand that can be used to synthesize PROTAC degraders targeting ALK (HY-122582). ALK ligand-2 is applicable to research related to non-small cell lung cancer, anaplastic large cell lymphoma, and neuroblastoma.

For research use only. We do not sell to patients.

CAS No.: 2230198-74-8
Formula: C₂₉H₃₇ClN₆O₅S
Molecular Weight:617.16

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Please store the product under the recommended conditions in the Certificate of Analysis.

ALK ligand-2 Chemical Structure

CAS No.: 2230198-74-8

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Description

Chemical Information

CAS No. 2230198-74-8
Molecular Weight 617.16
Formula C₂₉H₃₇ClN₆O₅S
SMILES

COC1=CC(N2CCN(C(OC(C)(C)C)=O)CC2)=CC=C1NC3=NC=C(Cl)C(NC4=CC=CC=C4S(=O)(C(C)C)=O)=N3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Powell CE, et al.. Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK). Journal of medicinal chemistry. 2018 May 10;61(9):4249-4255. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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