BODIPY 493/503
Based on 107 publication(s) in Google Scholar
BODIPY493/503 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells. Maximum excitation/emission wavelength: 493/503 nm.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.56%
- CAS No.: 121207-31-6
- 화학식: C14H17BF2N2
- 분자량:262.11
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보관:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications Citing Use of MedChemExpress (MCE) BODIPY 493/503
More- Signal Transduct Target Ther. 2025 Dec 8;10(1):398. [Abstract]
- Cell. 2026 Apr 30;189(9):2633-2647.e24. [Abstract]
- Cell Metab. 2025 Oct 24:S1550-4131(25)00435-8. [Abstract]
- Immunity. 2023 Nov 14;56(11):2542-2554.e7. [Abstract]
- Drug Resist Updat. 2026 May:86:101379. [Abstract]
- Nat Metab. 2025 Sep 23. [Abstract]
- Nat Commun. 2026 May 11;17(1):4190. [Abstract]
- Nat Commun. 2025 Dec 12;16(1):11092. [Abstract]
- Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]
- Nat Commun. 2023 Dec 21;14(1):8428. [Abstract]
- Autophagy. 2026 Mar 11:1-18. [Abstract]
- Autophagy. 2026 Feb 4:1-25. [Abstract]
- Adv Sci (Weinh). 2026 Mar 26:e19791. [Abstract]
- Adv Sci (Weinh). 2025 Nov 9:e14291. [Abstract]
- Adv Sci (Weinh). 2025 Nov 9:e08571. [Abstract]
- Adv Sci (Weinh). 2025 Nov 20:e19690. [Abstract]
- Adv Sci (Weinh). 2025 May 14:e2416419. [Abstract]
- Adv Sci (Weinh). 2025 Apr 26:e2417715. [Abstract]
- J Adv Res. 2026 Mar 21.
- J Exp Clin Cancer Res. 2025 Nov 25;44(1):310. [Abstract]
- J Nanobiotechnology. 2025 Jul 4;23(1):485. [Abstract]
- Metabolism. 2023 Aug:145:155579. [Abstract]
- J Hazard Mater. 2025 Jul 9:496:139198. [Abstract]
- Environ Sci Technol. 2025 Jan 14;59(1):268-278. [Abstract]
- Pharmacol Res. 2024 May 28:205:107235. [Abstract]
- Mater Today Bio. 2026 Jan 14:37:102808. [Abstract]
- Mater Today Bio. 2025 Jul 28:34:102134. [Abstract]
- Int J Surg. 2026 Jan 23. [Abstract]
- Int J Biol Sci. 2026 Jan 1;22(2):876-894. [Abstract]
- Int J Biol Sci. 2025 Mar 31;21(6):2707-2724. [Abstract]
- Cell Death Dis. 2025 Nov 24;16(1):854. [Abstract]
- Sci China Life Sci. 2025 Aug 1. [Abstract]
- Cell Commun Signal. 2025 Nov 28;23(1):514. [Abstract]
- Cell Commun Signal. 2024 Dec 21;22(1):616. [Abstract]
- Int J Biol Macromol. 2026 Jan;335(Pt 2):149182. [Abstract]
- Int J Biol Macromol. 2025 Jan 28:301:140458. [Abstract]
- Acta Pharmacol Sin. 2025 Nov 3. [Abstract]
- Phytomedicine. 2026 Apr:153:157977. [Abstract]
- Phytomedicine. 2026 Apr:153:157937. [Abstract]
- Phytomedicine. 2026 Mar:152:157830. [Abstract]
- Phytomedicine. 2025 Jun 22:145:156992. [Abstract]
- Phytomedicine. 2025 Feb 2:139:156445. [Abstract]
- Free Radic Biol Med. 2025 Oct 23:S0891-5849(25)01299-7. [Abstract]
- Food Chem X. 2024 Jun 28:23:101603. [Abstract]
- Br J Pharmacol. 2026 Jun;183(11):2675-2694. [Abstract]
- Environ Res. 2024 May 15:249:118402. [Abstract]
- Biomed Pharmacother. 2025 Nov 28:193:118831. [Abstract]
- J Transl Med. 2025 Jul 1;23(1):716. [Abstract]
- Oncogene. 2025 Sep 13. [Abstract]
- Oncogene. 2025 Sep;44(34):3096-3112. [Abstract]
- Aging Cell. 2024 Jun 19:e14256. [Abstract]
- Cell Rep. 2026 Mar 24;45(4):117193. [Abstract]
- Anal Chem. 2025 Oct 28;97(42):23555-23568. [Abstract]
- Mol Metab. 2026 Apr:106:102341. [Abstract]
- J Agric Food Chem. 2025 May 28;73(21):13006-13020. [Abstract]
- Cell Mol Life Sci. 2024 Sep 11;81(1):398. [Abstract]
- Ecotoxicol Environ Saf. 2026 Mar 15:313:119980. [Abstract]
- Food Biosci. 2026 Mar 6.
- Transl Res. 2024 May 9:271:26-39. [Abstract]
- Cell Prolif. 2025 Aug 27:e70118. [Abstract]
- Biochem Pharmacol. 2024 Jun:224:116240. [Abstract]
- Chem Biol Interact. 2026 Apr 25:429:111957. [Abstract]
- Food Funct. 2024 Sep 30;15(19):9863-9879. [Abstract]
- Food Funct. 2024 Aug 12;15(16):8544-8561. [Abstract]
- Cells. 2026 Mar 4;15(5):461. [Abstract]
- Int J Pharm. 2025 Jan 7:125190. [Abstract]
- Int J Oncol. 2025 Feb;66(2):15. [Abstract]
- J Nutr Biochem. 2025 Jan:135:109772. [Abstract]
- mBio. 2026 Apr 8;17(4):e0336825. [Abstract]
- Am J Physiol Cell Physiol. 2025 Oct 1;329(4):C1268-C1282. [Abstract]
- Int Immunopharmacol. 2025 Sep 23:162:115145. [Abstract]
- Int Immunopharmacol. 2024 Sep 27;142(Pt B):113258. [Abstract]
- mBio. 2024 Feb 14;15(2):e0319723. [Abstract]
- J Dairy Sci. 2025 Apr 11:S0022-0302(25)00233-4. [Abstract]
- Biochim Biophys Acta Mol Basis Dis. 2026 Jan 26;1872(4):168173. [Abstract]
- Drug Dev Res. 2025 Aug;86(5):e70129. [Abstract]
- J Cell Mol Med. 2025 May;29(9):e70416. [Abstract]
- FASEB J. 2025 May 15;39(9):e70608. [Abstract]
- Am J Physiol Heart Circ Physiol. 2025 Nov 1;329(5):H1267-H1277. [Abstract]
- iScience. 2025 Jul 25;28(8):113097. [Abstract]
- J Funct Foods. 2024 Oct.
- Sci Rep. 2025 Jul 1;15(1):21802. [Abstract]
- Aquaculture. 2025 Feb 15.
- J Virol. 2024 Sep 10:e0069524. [Abstract]
- Aquac Rep. 2026 Mar 25.
- Cell Signal. 2026 Jun:142:112454. [Abstract]
- Metabolites. 2025 Dec 4;15(12):781. [Abstract]
- Metabolites. 2025 May 14;15(5):324. [Abstract]
- BMC Genomics. 2025 May 8;26(1):457. [Abstract]
- Appl Biochem Biotechnol. 2025 Sep 2. [Abstract]
- Mol Carcinog. 2025 Dec 15. [Abstract]
- Biol Reprod. 2024 Jun 27:ioae085. [Abstract]
- J Anim Sci. 2026 Jan 8:104:skag058. [Abstract]
- J Biochem Mol Toxicol. 2024 Nov;38(11):e70001. [Abstract]
- Dev Comp Immunol. 2025 Jan 21:105324. [Abstract]
- Biochem Biophys Res Commun. 2023 Nov 12:681:165-172. [Abstract]
- bioRxiv. 2026 May 8:2026.05.05.723030. [Abstract]
- Res Sq. 2026 Mar 13.
- SSRN. 2025 Dec 5.
- SSRN. 2025 Oct 9.
- SSRN. 2025 May 15.
- bioRxiv. 2024 October 29.
- Eng Regen. 2024 Sep.
- SSRN. 2024 Feb 13.
- Research Square Preprint. 2023 Oct 16.
- Research Square Preprint. 2023 Oct 16.
- Research Square Preprint. 2023 Sep 5.
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Cell Imaging/Staining
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Cell Imaging/Staining
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IF
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IF
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Cell Imaging/Staining
Biological Activity
Guide (The following is our recommended protocol. This protocol is only a guide and should be modified according to your specific needs).
1. Preparation of BODIPY 493/503 working solution
1.1 Preparation of the stock solution
Dissolve 1 mg BODIPY 493/503 in 382 μL DMSO to obtain 10 mM of stock solution.
Note: It is recommended to store the stock solution at -20°C or -80°C, keep away from light and avoid repetitive freeze-thaw cycles.
1.2 Preparation of BODIPY 493/503 working solution
Dilute the stock solution in serum-free cell culture medium or PBS to obtain 1-10 μM of working solution.
Note: Please adjust the concentration of BODIPY 493/503 working solution according to the actual situation.
2. Cell staining
2.1 Suspension cells (6-well plate)
2.1.1 Centrifuge at 1000 g at 4°C for 3-5 min and then discard the supernatant. Wash twice with PBS, 5 min each time.The cell density is 1×106/mL.
2.1.2 Add 1 mL of working solution, and then incubate at room temperature for 5-30 min.
2.1.3 Centrifuge at 400 g at 4°C for 3-4 min and then discard the supernatant.
2.1.4 Wash twice with PBS, 5 min each time.
2.1.5 Resuspend cells with serum-free cell culture medium or PBS. Observation by fluorescence microscopy or flow cytometry.
2.2 Adherent cells
2.2.1 Culture adherent cells on sterile coverslips.
2.2.2 Remove the coverslip from the medium and aspirate excess medium.
2.2.3 Add 100 μL of working solution, gently shake it to completely cover the cells,and then incubate at room temperature for 5-30 min.
2.2.4 Wash twice with medium, 5 min each time. Observation by fluorescence microscopy or flow cytometry.
3. Precautions
3.1 Please adjust the concentration of BODIPY 493/503 working solution according to the actual situation.
3.2 Experiments suggest a positive control, incubate the control group cells with 30 μM oleic acid for 8 h and then perform subsequent experiments.
3.3 This product is only for R&D use, not for drug, household, or others.
3.4 For your safety and health, please wear a lab coat and disposable gloves to operate.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
503
493
Chemical Information
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CAS No. 121207-31-6
-
Appearance Solid
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분자량 262.11
-
화학식 C14H17BF2N2
-
Color Brown to reddish brown
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SMILES
[F-][B+3]1([N]2=C(C)C=C(C)C2=C(C)C3=C(C)C=C(C)[N-]31)[F-]
-
Synonyms
Pyrromethene 546
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (107)
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Journal Impact Factor
-
Most Recent
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Signal Transduct Target Ther
Lysophosphatidylethanolamine 18:1 drives clear cell renal cell carcinoma by stabilizing SIRT6 to reprogram lipid metabolism. [Abstract]2025 Dec 8;10(1):398. PMID: 41354870 -
Cell
2026 Apr 30;189(9):2633-2647.e24. PMID: 41806834 -
Cell Metab
Induction of a metabolic switch from glucose to ketone metabolism programs ketogenic diet-induced therapeutic vulnerability in lung cancer. [Abstract]2025 Oct 24:S1550-4131(25)00435-8. PMID: 41138721 -
Immunity
Retinoid X receptor gamma dictates the activation threshold of group 2 innate lymphoid cells and limits type 2 inflammation in the small intestine. [Abstract]2023 Nov 14;56(11):2542-2554.e7. PMID: 37714152 -
Drug Resist Updat
Stabilin-1+ lipid-associated macrophages promote lung adenocarcinoma liver metastasis and osimertinib resistance through impairing macrophage phagocytosis via SIRPα-CD47 axis. [Abstract]2026 May:86:101379. PMID: 41719890 -
Nat Metab
Cholesterol metabolic reprogramming mediates microglia-induced chronic neuroinflammation and hinders neurorestoration following stroke. [Abstract]2025 Sep 23. PMID: 40987840 -
Nat Commun
Ascites protects against ferroptosis and enables the peritoneal growth of ovarian cancer. [Abstract]2026 May 11;17(1):4190. PMID: 42115216 -
Nat Commun
2025 Dec 12;16(1):11092. PMID: 41387436 -
Nat Commun
Copy number amplification of FLAD1 promotes the progression of triple-negative breast cancer through lipid metabolism. [Abstract]2025 Feb 1;16(1):1241. PMID: 39890808
BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]
Neutral lipids stained with the BODIPY 493/503 (0.2 μg/mL; 30 min) probe in the control and FLAD1 knockdown SUM159 cells expressing the control vector, WT FLAD1 or FLAD1-R530C. Scale bars, 20 μm.
BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]
Neutral lipids stained with the BODIPY 493/503 (0.2 μg/mL; 30 min) probe in the control and FLAD1 knockdown in the HCC1806 cells expressing the control vector, WT FLAD1 or FLAD1-R530C. Scale bars, 20 μm.
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Nat Commun
2023 Dec 21;14(1):8428. PMID: 38129407 -
Autophagy
2026 Mar 11:1-18. PMID: 41810751 -
Autophagy
The PI4K2A-OSBPL6/ORP6-PS axis mediates lysosomal membrane repair to restore neuronal lipid homeostasis and promote neuronal survival after spinal cord injury. [Abstract]2026 Feb 4:1-25. PMID: 41556583 -
Adv Sci (Weinh)
SMAD4 Palmitoylation Drives a Metabolic-Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer. [Abstract]2026 Mar 26:e19791. PMID: 41885390 -
Adv Sci (Weinh)
GSK3β-Regulated Lipolysis is Required for Histone Acetylation and Decidualization in Early Pregnancy. [Abstract]2025 Nov 9:e14291. PMID: 41208306 -
Adv Sci (Weinh)
Thyroid Hormone Receptor β1 and PGC1α Coordinately Regulate OPA1/MFN2-Mediated Mitochondrial Fusion and UCP1-Mediated Lipid Browning in ccRCC. [Abstract]2025 Nov 9:e08571. PMID: 41208194 -
Adv Sci (Weinh)
A Supramolecular Nanoscavengers: Based "Cargo-Exchange" Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy. [Abstract]2025 Nov 20:e19690. PMID: 41267386 -
Adv Sci (Weinh)
MTFR2-Mediated Fission Drives Fatty Acid and Mitochondrial Co-Transfer from Hepatic Stellate Cells to Tumor Cells Fueling Oncogenesis. [Abstract]2025 May 14:e2416419. PMID: 40365837 -
Adv Sci (Weinh)
LncRNA-MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid-Liquid Phase Separation. [Abstract]2025 Apr 26:e2417715. PMID: 40285575 -
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J Exp Clin Cancer Res
Pharmacological induction of acetyl-CoA carboxylase 1 autophagic degradation attenuates lipid accumulation and cholangiocarcinoma progression. [Abstract]2025 Nov 25;44(1):310. PMID: 41291880 -
J Nanobiotechnology
SIRT5-modified human umbilical cord mesenchymal stem cells loaded with antioxidant polydopamine nanozyme enhance parpi resistance in ovarian cancer via fatty acid metabolism reprogramming. [Abstract]2025 Jul 4;23(1):485. PMID: 40616128 -
Metabolism
DR region of NKAα1 is a target to ameliorate hepatic lipid metabolism disturbance in obese mice. [Abstract]2023 Aug:145:155579. PMID: 37127227 -
J Hazard Mater
2025 Jul 9:496:139198. PMID: 40652855 -
Environ Sci Technol
Arsenic Exposure Triggers Nonalcoholic Fatty Liver Disease through Repressing S-Adenosylmethionine-Dependent Histone Methylation in Rats. [Abstract]2025 Jan 14;59(1):268-278. PMID: 39746780
BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Environ Sci Technol. 2025 Jan 14;59(1):268-278. [Abstract]
BODIPY 493/503 (2 μM; 15 min). BODIPY 493/503 staining of lipids in HepG2 cells.
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Pharmacol Res
USP7 promotes cardiometabolic disorders and mitochondrial homeostasis dysfunction in diabetic mice via stabilizing PGC1β. [Abstract]2024 May 28:205:107235. PMID: 38815879 -
Mater Today Bio
Bioinspired lipid droplets nanoplatform for periodontitis therapy: Integrated antibacterial, mitochondrial repair, and immunomodulatory functions. [Abstract]2026 Jan 14:37:102808. PMID: 41624519 -
Mater Today Bio
An AIE-active type I/II photosensitizer with mitochondria-to-nuclei cascade targeting for highly efficient photodynamic cancer therapy. [Abstract]2025 Jul 28:34:102134. PMID: 40791798 -
Int J Surg
Single-cell transcriptomics uncovers malignant potential of gallbladder adenomyomatosis and identifies PRDX1+ immunosuppressive macrophages in gallbladder carcinoma. [Abstract]2026 Jan 23. PMID: 41570280 -
Int J Biol Sci
Hepatocyte SAMHD1 Deficiency Attenuates Hepatic Steatosis via Suppression of SREBP Activation in a Mouse Model of Metabolic-Associated Steatotic Liver Disease. [Abstract]2026 Jan 1;22(2):876-894. PMID: 41522335 -
Int J Biol Sci
NAMPT Impairs Vascular Permeability in Periodontitis by Influencing FASN-mediated Lipogenesis. [Abstract]2025 Mar 31;21(6):2707-2724. PMID: 40303304 -
Cell Death Dis
Necrotic and apoptotic adipocytes in the hypoxic tumor microenvironment supply triglycerides to induce cisplatin resistance in the metastatic lymph nodes of head and neck carcinoma. [Abstract]2025 Nov 24;16(1):854. PMID: 41285714 -
Sci China Life Sci
Contribution of orchids to the carbon budget of fungi in germinating seeds of Gymnadenia conopsea. [Abstract]2025 Aug 1. PMID: 40762940 -
Cell Commun Signal
Regulatory role of sirtuin-1 by targeting MDM2 to mitochondria-associated membranes formation in the treatment of NAFLD. [Abstract]2025 Nov 28;23(1):514. PMID: 41316250 -
Cell Commun Signal
Exosomal ANXA2 facilitates ovarian cancer peritoneal metastasis by activating peritoneal mesothelial cells through binding with TLR2. [Abstract]2024 Dec 21;22(1):616. PMID: 39709496 -
Int J Biol Macromol
Targeting glutaryl-CoA dehydrogenase-driven acetyl coenzyme A acetyltransferase 2 crotonylation dysregulates cholesterol metabolism in pancreatic cancer cells. [Abstract]2026 Jan;335(Pt 2):149182. PMID: 41285334 -
Int J Biol Macromol
Cholic acid inhibits ovarian steroid hormone synthesis and follicular development through farnesoid X receptor signaling in mice. [Abstract]2025 Jan 28:301:140458. PMID: 39884637
BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2025 Jan 28:301:140458. [Abstract]
BODIPY 493/503 (2 μg/mL; 15 min). At the end of culturing, cells were fixed and stained with BODIPY 493/503, and images were taken under a fluorescence microscope; scale bar: 200 μm.
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Acta Pharmacol Sin
Sino-C, a novel sinomenine derivative, induces cell death by disrupting cholesterol homeostasis in colorectal cancer cells. [Abstract]2025 Nov 3. PMID: 41184618 -
Phytomedicine
Nobiletin alleviates alcoholic fatty liver disease by regulating lipid metabolism and oxidative stress via Ephx1 and Sult1a1. [Abstract]2026 Apr:153:157977. PMID: 41720003 -
Phytomedicine
Cyasterone regulates lipid metabolism and autophagy mediated by the AMPK signaling pathway to improve KOA synovitis. [Abstract]2026 Apr:153:157937. PMID: 41687535 -
Phytomedicine
Qing Hua Yu Du formula ameliorates alcoholic hepatic fibrosis by regulating MAPK/TLR4-MyD88 inflammatory pathways, restoring hepatic metabolism and modulating gut microbiota. [Abstract]2026 Mar:152:157830. PMID: 41570783 -
Phytomedicine
Alisol B ameliorated metabolic dysfunction-associated steatotic liver disease via regulating purine metabolism and restoring the gut microbiota disorders. [Abstract]2025 Jun 22:145:156992. PMID: 40582207 -
Phytomedicine
3-Hydroxypropionaldehyde modulates tryptophan metabolism to activate AhR signaling and alleviate ethanol-induced liver injury. [Abstract]2025 Feb 2:139:156445. PMID: 39922148
BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Feb 2:139:156445. [Abstract]
BODIPY 493/503 (1 µM; 1 h). Representative images and quantitative results of BODIPY staining (scale bars, 20 µm) in AML-12 cells. (n = 5 per group)
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Free Radic Biol Med
V8, a lysosomotropic wogonin derivative, alleviates hepatic steatosis by modulating GDF15-dependent mitochondrial homeostasis. [Abstract]2025 Oct 23:S0891-5849(25)01299-7. PMID: 41138960 -
Food Chem X
Plant-derived leaf vein scaffolds for the sustainable production of dog cell-cultured meat. [Abstract]2024 Jun 28:23:101603. PMID: 39100247
BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Food Chem X. 2024 Jun 28:23:101603. [Abstract]
BODIPY 493/503 (5 µM; 30 min). Representative images of immunofluorescence staining of MSCs-derived myotubes on NLV scaffolds after 7 days in differentiation media. Green: Desmin; Blue: Veins. Scale bars: 100 μm.
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Br J Pharmacol
Fenofibrate potentiates the therapeutic efficacy of EZH2 inhibitors on melanoma via TRIM21- and OTUD4-mediated EZH2 ubiquitination. [Abstract]2026 Jun;183(11):2675-2694. PMID: 41652905 -
Environ Res
Microcystin-RR promote lipid accumulation through CD36 mediated signal pathway and fatty acid uptake in HepG2 cells. [Abstract]2024 May 15:249:118402. PMID: 38309560 -
Biomed Pharmacother
Differential adipose tissue remodeling and metabolic effects of dolutegravir and bictegravir: implications for HIV therapy. [Abstract]2025 Nov 28:193:118831. PMID: 41317481 -
J Transl Med
Identification of matrix stiffness-related molecular subtypes in HCC via integrating multi-omics analysis and machine learning algorithms. [Abstract]2025 Jul 1;23(1):716. PMID: 40598539 -
Oncogene
FOXA2 sensitizes endometrial carcinoma to progestin-mediated conservative therapy by triggering PR transcriptional activation. [Abstract]2025 Sep 13. PMID: 40946101 -
Oncogene
ACSL5 regulated acetyl-CoA to promote bladder cancer cellular senescence via 53BP1 acetylation. [Abstract]2025 Sep;44(34):3096-3112. PMID: 40595416 -
Aging Cell
Aging-induced short-chain acyl-CoA dehydrogenase promotes age-related hepatic steatosis by suppressing lipophagy. [Abstract]2024 Jun 19:e14256. PMID: 38898632 -
Cell Rep
Astrocytic AEBP1-NPAS3-LIPA pathway coordinates cholesterol homeostasis to regulate Alzheimer's pathology. [Abstract]2026 Mar 24;45(4):117193. PMID: 41880326 -
Anal Chem
Advanced Clinical Diagnosis of Malaria Using a Simple Red-Emissive Smart Fluorescent Probe. [Abstract]2025 Oct 28;97(42):23555-23568. PMID: 41103010 -
Mol Metab
2026 Apr:106:102341. PMID: 41747880 -
J Agric Food Chem
Copper-Induced DRP1 Activation Disrupts Mitochondrial-Lipid Droplet Contact to Promote Hepatic Steatosis. [Abstract]2025 May 28;73(21):13006-13020. PMID: 40387024 -
Cell Mol Life Sci
MicroRNA-411-5p alleviates lipid deposition in metabolic dysfunction-associated steatotic liver disease by targeting the EIF4G2/FOXO3 axis. [Abstract]2024 Sep 11;81(1):398. PMID: 39261317
BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Cell Mol Life Sci. 2024 Sep 11;81(1):398. [Abstract]
BODIPY staining (BODIPY 493/503 (5 µM; 30 min)) of PA-induced steatosis hepatocytes.
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Ecotoxicol Environ Saf
F-53B triggers sleep disorders via very long-chain ceramide accumulation in Drosophila neurons. [Abstract]2026 Mar 15:313:119980. PMID: 41793920 -
-
Transl Res
Counteracting TGM2 by a Fibroin peptide ameliorated Adriamycin-induced nephropathy via regulation of lipid metabolism through PANX1-PPAR α/PANK1 pathway. [Abstract]2024 May 9:271:26-39. PMID: 38734063 -
Cell Prolif
Development of NAFLD-Specific Human Liver Organoid Models on a Microengineered Array Chip for Semaglutide Efficacy Evaluation. [Abstract]2025 Aug 27:e70118. PMID: 40873114 -
Biochem Pharmacol
Sesamin ameliorates nonalcoholic hepatic steatosis by inhibiting CD36-mediated hepatocyte lipid accumulation in vitro and in vivo. [Abstract]2024 Jun:224:116240. PMID: 38679210 -
Chem Biol Interact
Cyflumetofen induces hepatic steatosis and disrupts lipid metabolism in zebrafish larvae. [Abstract]2026 Apr 25:429:111957. PMID: 41654006 -
Food Funct
2024 Sep 30;15(19):9863-9879. PMID: 39246047 -
Food Funct
Selenoprotein H mediates low selenium-related cognitive decline through impaired oligodendrocyte myelination with disrupted hippocampal lipid metabolism in female mice. [Abstract]2024 Aug 12;15(16):8544-8561. PMID: 39072440 -
Cells
The CDO1-ACSM3 Axis Mediates Renal Tubule Lipid Deposition and Injury by Causing Mitochondrial Dysfunction in Lupus Nephritis. [Abstract]2026 Mar 4;15(5):461. PMID: 41827894 -
Int J Pharm
FAP-targeting biomimetic nanosystem to restore the activated cancer-associated fibroblasts to quiescent state for breast cancer radiotherapy. [Abstract]2025 Jan 7:125190. PMID: 39788396 -
Int J Oncol
SLC25A1 promotes lymph node metastasis of esophageal squamous cell carcinoma by regulating lipid metabolism. [Abstract]2025 Feb;66(2):15. PMID: 39821659 -
J Nutr Biochem
A natural small molecule pinocembrin resists high-fat diet-induced obesity through GPR120-ERK1/2 pathway. [Abstract]2025 Jan:135:109772. PMID: 39313008 -
mBio
African swine fever virus hijacks lipolysis induced by chaperone-mediated autophagy to upregulate fatty acid β-oxidation and promote viral replication. [Abstract]2026 Apr 8;17(4):e0336825. PMID: 41801037 -
Am J Physiol Cell Physiol
2025 Oct 1;329(4):C1268-C1282. PMID: 40953040 -
Int Immunopharmacol
Breviscapine regulates lipid metabolism of microglia via the ADORA1/PPARα/ACOX1 pathway to promote spinal cord injury recovery. [Abstract]2025 Sep 23:162:115145. PMID: 40628044 -
Int Immunopharmacol
Liraglutide alleviates ferroptosis in renal ischemia reperfusion injury via inhibiting macrophage extracellular trap formation. [Abstract]2024 Sep 27;142(Pt B):113258. PMID: 39340991 -
mBio
PEDV inhibits HNRNPA3 expression by miR-218-5p to enhance cellular lipid accumulation and promote viral replication. [Abstract]2024 Feb 14;15(2):e0319723. PMID: 38259103
BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: mBio. 2024 Feb 14;15(2):e0319723. [Abstract]
BODIPY 493/503 (10 min). Marc-145 cells were transfected with siSREBF1 or siNC and then infected with PEDV (MOI = 1) for 24 h. The contents of cellular lipid droplets (green) and the nuclei (blue) were detected by immunofluorescence assay. Scale bar, 10 µm. The fluorescence intensity of lipids was analyzed with ImageJ.
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J Dairy Sci
Effects of maternal blood beta-hydroxybutyrate on brown adipose tissue functions and thermogenic and metabolic health in neonatal calves. [Abstract]2025 Apr 11:S0022-0302(25)00233-4. PMID: 40222674 -
Biochim Biophys Acta Mol Basis Dis
Circ_0075691 regulates lipid metabolism in granulosa cells by interacting with EIF4A3 to promote PTGS2 mRNA stability. [Abstract]2026 Jan 26;1872(4):168173. PMID: 41605366 -
Drug Dev Res
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용액&용해도
DMF : 5.56 mg/mL (21.21 mM; ultrasonic and warming and heat to 60°C)
DMSO : 5 mg/mL (19.08 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
순도&문서
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Data Sheet (285 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / DMF | 1 mM | 3.8152 mL | 19.0760 mL | 38.1519 mL | 95.3798 mL |
| 5 mM | 0.7630 mL | 3.8152 mL | 7.6304 mL | 19.0760 mL | |
| 10 mM | 0.3815 mL | 1.9076 mL | 3.8152 mL | 9.5380 mL | |
| 15 mM | 0.2543 mL | 1.2717 mL | 2.5435 mL | 6.3587 mL | |
| DMF | 20 mM | 0.1908 mL | 0.9538 mL | 1.9076 mL | 4.7690 mL |