CL 5343 (Standard)
CL 5343 (Standard) is the analytical standard of CL 5343. This product is intended for research and analytical applications. CL 5343 (5-Amino-1,3,4-thiadiazole-2-sulfonamide) is an inhibitor of human carbonic anhydrase B (HCA-B). CL 5343 can serve as a CA9 ligand to achieve the targeted delivery of maytansinoid to the cell membrane of SKRC52 renal cancer cells.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 14949-00-9
- 화학식: C2H4N4O2S2
- 분자량:180.21
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 14949-00-9
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분자량 180.21
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화학식 C2H4N4O2S2
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SMILES
O=S(C1=NN=C(N)S1)(N)=O
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Synonyms
5-Amino-1,3,4-thiadiazole-2-sulfonamide (Standard)
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Pesando JM, et al. Proton magnetic resonance studies of carbonic anhydrase. III. Binding of sulfonamides. Biochemistry. 1975;14(4):689-693. [Content Brief]
[2]. Pérez-Herrero E, et al. The reversed intra-and extracellular pH in tumors as a unified strategy to chemotherapeutic delivery using targeted nanocarriers[J]. Acta Pharmaceutica Sinica B, 2021, 11(8): 2243-2264. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)