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Cat. No.: HY-161691

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EBOV-IN-9

EBOV-IN-9 (compound 2b) is Diphyllin derivative that blocks Ebola viral entry with an EC₅₀ of 40 nM. EBOV-IN-9 against EBOV-infected monocyte-derived macrophages with an EC₅₀ of 107 nM.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₅H₂₂O₈
분자량:450.44

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

EBOV-IN-9 Chemical Structure

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

EBOV-IN-9 (compound 2b) is Diphyllin derivative that blocks Ebola viral entry with an EC₅₀ of 40 nM. EBOV-IN-9 against EBOV-infected monocyte-derived macrophages with an EC₅₀ of 107 nM^[1].

IC₅₀ & Target

EBOV

All Filovirus Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	CC₅₀	>80 μM Compound: 2b	Cytotoxicity against HEK293 cells incubated for 72 hrs by MTT assay Cytotoxicity against HEK293 cells incubated for 72 hrs by MTT assay	[PMID: 38875806]

Chemical Information

분자량 450.44
화학식 C₂₅H₂₂O₈
SMILES

O=C1OCC2=C(OC3COCC3)C4=CC(OC)=C(OC)C=C4C(C5=CC=C(OCO6)C6=C5)=C12
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. lLaura M. Sanford, et al. Evaluation of Potency and Metabolic Stability of Diphyllin-derived Vacuolar-ATPase Inhibitors. European Journal of Medicinal Chemistry. 28 May 2024, 116537.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

EBOV-IN-9

All Filovirus Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

EBOV-IN-9 Related Classifications

HY-161691 Related Classifications