Mal-NH-PEG8-Boc
Based on 1 Customer Validation
Mal-NH-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.37%
- 화학식: C30H52N2O13
- 분자량:648.74
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보관:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Oil
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분자량 648.74
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화학식 C30H52N2O13
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Color Colorless to light yellow
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SMILES
O=C1C=CC(N1CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O)=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
용액&용해도
DMSO : 500 mg/mL (770.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5414 mL | 7.7072 mL | 15.4145 mL | 38.5362 mL |
| 5 mM | 0.3083 mL | 1.5414 mL | 3.0829 mL | 7.7072 mL | |
| 10 mM | 0.1541 mL | 0.7707 mL | 1.5414 mL | 3.8536 mL | |
| 15 mM | 0.1028 mL | 0.5138 mL | 1.0276 mL | 2.5691 mL | |
| 20 mM | 0.0771 mL | 0.3854 mL | 0.7707 mL | 1.9268 mL | |
| 25 mM | 0.0617 mL | 0.3083 mL | 0.6166 mL | 1.5414 mL | |
| 30 mM | 0.0514 mL | 0.2569 mL | 0.5138 mL | 1.2845 mL | |
| 40 mM | 0.0385 mL | 0.1927 mL | 0.3854 mL | 0.9634 mL | |
| 50 mM | 0.0308 mL | 0.1541 mL | 0.3083 mL | 0.7707 mL | |
| 60 mM | 0.0257 mL | 0.1285 mL | 0.2569 mL | 0.6423 mL | |
| 80 mM | 0.0193 mL | 0.0963 mL | 0.1927 mL | 0.4817 mL | |
| 100 mM | 0.0154 mL | 0.0771 mL | 0.1541 mL | 0.3854 mL |
Mal-NH-PEG8-Boc Related Classifications
HY-138447 Related Classifications
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