Delta-like protein 3/DLL3 Protein, Mouse (HEK293, His)

Delta-like protein 3 (DLL3) inhibits primary neurogenesis and directs neurons towards specific differentiation pathways. It also contributes to the formation of somite boundaries in the paraxial mesoderm segmentation. DLL3's importance in developmental processes is highlighted by its ability to bind and activate Notch-1 or other Notch receptors. Delta-like protein 3/DLL3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Delta-like protein 3/DLL3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Delta-like protein 3/DLL3 Protein, Mouse (HEK293, His) is 464 a.a., with molecular weight of 52-60 kDa.

Delta-like protein 3 (DLL3) functions as an inhibitor of primary neurogenesis and may play a crucial role in diverting neurons along a specific differentiation pathway. Additionally, DLL3 is involved in the formation of somite boundaries during the segmentation of the paraxial mesoderm. Its ability to bind and activate Notch-1 or other Notch receptors underscores its significance in regulating developmental processes.

Immobilized Mouse DLL3, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC₅₀ of 7.7 ng/ml determined by ELISA.

Mouse

HEK293

C-His

O88516 (A25-R488)

13389  [NCBI]

52-60 kDa

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.