KGF-2/FGF-10 Protein, Rat
Based on 1 Customer Validation
KGF-2/FGF-10 Protein is vital in regulating embryonic development, crucial for cell proliferation, differentiation, and normal branching morphogenesis. Essential for organ and tissue development, it interacts with FGFR1 and FGFR2, integral to its signaling. The protein may contribute to wound healing and engages with FGFBP1, indicating regulatory interactions within FGF signaling pathways. KGF-2/FGF-10 Protein, Rat is the recombinant rat-derived KGF-2/FGF-10 protein, expressed by E. coli , with tag free.
- Species: Rat
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
KGF-2/FGF-10 Protein is vital in regulating embryonic development, crucial for cell proliferation, differentiation, and normal branching morphogenesis. Essential for organ and tissue development, it interacts with FGFR1 and FGFR2, integral to its signaling. The protein may contribute to wound healing and engages with FGFBP1, indicating regulatory interactions within FGF signaling pathways. KGF-2/FGF-10 Protein, Rat is the recombinant rat-derived KGF-2/FGF-10 protein, expressed by E. coli , with tag free.
The KGF-2/FGF-10 protein is critically involved in the regulation of embryonic development, playing a crucial role in cell proliferation and cell differentiation. It is indispensable for normal branching morphogenesis, a process essential for the development of various organs and tissues. Additionally, KGF-2/FGF-10 may contribute to wound healing mechanisms. It interacts with FGFR1 and FGFR2, two receptors implicated in its signaling pathways, and also interacts with FGFBP1, suggesting potential regulatory interactions with other proteins involved in FGF signaling.
Measured in a cell proliferation assay using 4MBr-5 rhesus monkey epithelial cells. The ED50 for this effect is 98.78 ng/mL, corresponding to a specific activity is 1.01×10^4 units/mg.
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Measured in a cell proliferation assay using 4MBr-5 rhesus monkey epithelial cells. The ED50 for this effect is 98.78 ng/mL, corresponding to a specific activity is 1.01×10^4 units/mg.
Technical Parameters
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Species Rat
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Source E. coli
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Tag Tag Free
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Accession
P70492 (Q37-S215)
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Gene ID25443
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Molecular Construction
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N-term
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FGF-10 (Q37-S215)
Accession # P70492 -
C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
rMuFGF-10; Fibroblast growth factor 10; Fgf10
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AA Sequence
QALGQDMVSPEATNSSSSSSSSSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS
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Predicted Molecular Mass
20 kDa
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Molecular Weight
Approximately 23 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
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≥ 95%, as determined by reducing SDS-PAGE.
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Product Properties
Lyophilized powder
Lyophilized from a 0.22 μm filtered concentrated solution in 20 mM Tris, 500 mM NaCl, pH 7.4, 5% trehalose.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (236 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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