FGF-10
FGF-10, also termed KGF-2, is the mesenchymal partner of epithelial FGFR2b and a key architect of branching organs. It controls limb-bud initiation, lung branching morphogenesis, lacrimal and salivary gland development, and hair follicle formation. Heterozygous FGF10 mutations cause lacrimo-auriculo-dento-digital (LADD) syndrome, and complete FGF10 deficiency underlies autosomal-recessive aplasia of the lacrimal and salivary glands. In adults, FGF-10 promotes epithelial repair in lung and cornea and is being explored as a therapy for chronic obstructive pulmonary disease and dry-eye disease. Recombinant FGF-10 is standard in lung organoid budding assays, epithelial culture and FGFR2b-specific binding studies.
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FGF-10 Recombinant Proteins (8)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
