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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
NHERF1
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "NHERF1" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P701153
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EBP50; NHERF; NHERF-1; NHERF1; NPHLOP2
Cat. No.: HY-RS09282
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NHERF1 Human Pre-designed siRNA Set A contains three designed siRNAs for NHERF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-150269
CAS No.: 2227017-46-9
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RS5517 is a specific PDZ1-domain antagonist of NHERF1 that prevented its ectopic nuclear entry. RS5517 can be used for the research of colorectal cancer [1] .
Cat. No.: HY-182624
CAS No.: 873841-43-1
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FJ9 is a NHERF1/PDZ inhibitor with human NHERF1 PDZ1 IC50 1540 μM, NHERF1 PDZ2 IC50 160 μM, and Frizzled-7-Dishevelled PDZ complex Ki 10 μM. FJ9 binds ligand-binding pockets of NHERF1 PDZ domains to block cognate ligand interactions, disrupts Frizzled-7-Dishevelled interactions, and down-regulates canonical Wnt signaling. FJ9 induces apoptosis in cancer cells with intact β-catenin signaling. FJ9 can be used for the research of non-small cell lung cancer, melanoma [1] .
Cat. No.: HY-P701153A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EBP50; NHERF; NHERF-1; NHERF1; NPHLOP2
Cat. No.: HY-P10226
CAS No.: 2717490-36-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
