93 Results for "

Nectin

" in MedChemExpress (MCE) Product Catalog:
Products (93)

93 Results for "Nectin" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99016
CAS No.: 1448664-46-7

Target:  

ADC Antibodies Nectin-4

Research Areas:  

Cancer

Enfortumab is a humanized derived anti-Nectin-4 antibody that can be conjugated with the highly efficient microtubule disruptor MMAE (HY-15162) to generate the antibody drug conjugate (ADC) Enfortumab vedotin-ejfv (HY-P99016A). Enfortumab can be used for the study of locally advanced and metastatic urothelial carcinoma .
1
1 Cited Publications
Cat. No.: HY-P99016B
CAS No.: 1346452-25-2

Research Areas:  

Cancer

Enfortumab vedotin-ejfv (solution) is an anti-Nectin-4 antibody-drug conjugate (ADC). Enfortumab vedotin-ejfv (solution) is a fully humanized IgG1 antibody conjugated to the microtubule disrupting agent MMAE (HY-15162) via a protease-cleavable Val-Cit linker. The antibody portion is Enfortumab (HY-P99016), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Nectin-4 is an adhesion protein involved in cellular processes and tumorigenesis, and Enfortumab vedotin-ejfv (solution) is indicated for the inhibition of locally advanced or metastatic urothelial carcinoma .
1
1 Cited Publications
Cat. No.: HY-P99016A
CAS No.: 1346452-25-2
Enfortumab vedotin-ejfv is an anti-Nectin-4 antibody-drug conjugate. Enfortumab vedotin-ejfv is a fully humanized IgG1 antibody conjugated to the microtubule disrupting agent MMAE (HY-15162) via a protease-cleavable Val-Cit linker. The antibody portion is Enfortumab (HY-P99016), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Nectin-4 is an adhesion protein involved in cellular processes and tumorigenesis, and Enfortumab vedotin-ejfv is indicated for the inhibition of locally advanced or metastatic urothelial carcinoma .
1
1 Cited Publications
Cat. No.: HY-P78084
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD155; HVED; NECL5; Necl-5; Nectin-like 5; PVR; PVS; Tage4; PVSFLJ25946; FLJ25946
Species:  
Source:  
Cat. No.: HY-147271
CAS No.: 2679821-39-5
Purity:  99.48%
Research Areas:  

Others

Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b) is an antibody-drug conjugate linker (ADC linker) that binds to Nectin-4 polypeptides conjugated to chemotherapeutic agents. Mal-PEG8-Val-Ala-PAB-Exatecan can be used for cancer research .
Cat. No.: HY-P991707
CAS No.: 3036556-50-7
Synonyms: SHR-A2102 antibody

Target:  

Nectin-4

Research Areas:  

Cancer

Notiretatug is a humanized IgG1κ antibody targeting Nectin-4. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001) .
Cat. No.: HY-P990977
CAS No.: 2862919-81-9
Synonyms: MW282 mAb

Target:  

Nectin-4

Research Areas:  

Inflammation/Immunology

HY-P990977 is an Nectin-4-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
Cat. No.: HY-P991742
Synonyms: 15A7.5; ETx-22 Antibody

Target:  

ADC Antibodies

Research Areas:  

Cancer

LY4101174 Antibody is an ADC antibody. LY4101174 is an antibody-drug conjugate (ADC) that targets the nectin-4 protein present on the surface of certain cancer cells. It can directly deliver a potent chemotherapy agent (Exatecan (HY-13631)) to the tumor site and is used for the study of advanced cancers, such as urothelial carcinoma, triple-negative breast cancer, and non-small cell lung cancer .
Cat. No.: HY-RS09175
Research Areas:  

Others

NECTIN2 Human Pre-designed siRNA Set A contains three designed siRNAs for NECTIN2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS18105
Research Areas:  

Others

Nectin2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nectin2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-178489
Target:  

Nectin-4

Research Areas:  

Cancer

BGC1614 is a Nectin-4-targeting bicyclic toxin conjugate (BTC) belonging to the category of peptide-drug conjugates (PDCs). BGC1614 exhibits strong targeted binding ability to Nectin-4, with an KD of 3.859 × 10 -7 M. BGC1614 exhibits superior antitumor efficacy in nude mice bearing PC-3 and N87 tumor xenografts. BGC1614 can be used for research related to Nectin-4-overexpressing tumors (such as prostate cancer, gastric cancer) .
Cat. No.: HY-RS09174
Research Areas:  

Others

NECTIN1 Human Pre-designed siRNA Set A contains three designed siRNAs for NECTIN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS09176
Research Areas:  

Others

NECTIN3 Human Pre-designed siRNA Set A contains three designed siRNAs for NECTIN3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS09177
Research Areas:  

Others

NECTIN4 Human Pre-designed siRNA Set A contains three designed siRNAs for NECTIN4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS20215
Research Areas:  

Others

Nectin1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nectin1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS21247
Research Areas:  

Others

Nectin4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nectin4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS27764
Research Areas:  

Others

Nectin4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Nectin4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24579
Research Areas:  

Others

Nectin2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Nectin2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS26721
Research Areas:  

Others

Nectin1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Nectin1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-P992133
CAS No.: 3049680-24-9
Synonyms: SYS6002 Antibody; CRB-701 Antibody

Target:  

ADC Antibodies Nectin-4

Research Areas:  

Cancer

Sutantatug (SYS6002 Antibody) is a monoclonal antibody targeting Nectin-4, and serves as the antibody moiety of the ADC CRB-701. Sutantatug is applicable to the research of Nectin-4-positive solid tumors, urothelial carcinoma and cervical cancer. The corresponding isotype control for Sutantatug is Human IgG1 kappa, Isotype Control (HY-P99001) .