5 Results for "

RLRs

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "RLRs" in MCE Product Catalog:

3
Ro 90-7501
Ro 90-7501
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3 Cited Publications
Cat. No.: HY-103241
CAS No.: 293762-45-5
Purity:  99.10%
Target:  

Amyloid-β ATM/ATR Phosphatase Apoptosis

Research Areas:  

Neurological Disease Cancer

Ro 90-7501 is an amyloid β42 (Aβ42) fibril assembly inhibitor that reduces Aβ42-induced cytotoxicity (EC50 of 2 μM). Ro 90-7501 inhibits ATM phosphorylation and DNA repair. RO 90-7501 selectively enhances toll-like receptor 3 (TLR3) and RIG-I-like receptor (RLR) ligand-induced IFN-β gene expression and antiviral response . Ro 90-7501 also inhibits protein phosphatase 5 (PP5) in a TPR-dependent manner . Ro 90-7501 has significant radiosensitizing effects on cervical cancer cells .
2
KIN1408
KIN1408
0 Images
2 Cited Publications
Cat. No.: HY-19961
CAS No.: 1903800-11-2
Target:  

Flavivirus Dengue Virus RIG-I-like receptor (RLR) HCV

Research Areas:  

Infection

KIN1408 is an agonist of the RIG-1-like receptor (RLR) pathway and exhibits a broad-spectrum antiviral activity. KIN1408 exhibits activity against HCV, influenza A, dengue virus 2, Ebola, Nipah, and Lassa viruses .
Ac-RLR-AMC
Ac-RLR-AMC
0 Images
Cat. No.: HY-135070
CAS No.: 929903-87-7
Synonyms: Ac-Arg-Leu-Arg-AMC
Target:  

Proteasome

Research Areas:  

Others

Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes .
Ac-RLR-AMC TFA
Ac-RLR-AMC TFA
0 Images
Cat. No.: HY-135070B
Synonyms: Ac-Arg-Leu-Arg-AMC TFA
Target:  

Proteasome

Research Areas:  

Others

Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) TFA is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes .
Ro 90-7501 (Standard)
Ro 90-7501 (Standard)
0 Images
Cat. No.: HY-103241R
CAS No.: 293762-45-5
Target:  

Reference Standards Amyloid-β ATM/ATR Phosphatase Apoptosis

Research Areas:  

Neurological Disease Cancer

Ro 90-7501 (Standard) is the analytical standard of Ro 90-7501 (HY-103241). This product is intended for research and analytical applications. Ro 90-7501 is an amyloid β42 (Aβ42) fibril assembly inhibitor that reduces Aβ42-induced cytotoxicity (EC50 of 2 μM). Ro 90-7501 inhibits ATM phosphorylation and DNA repair. RO 90-7501 selectively enhances toll-like receptor 3 (TLR3) and RIG-I-like receptor (RLR) ligand-induced IFN-β gene expression and antiviral response . Ro 90-7501 also inhibits protein phosphatase 5 (PP5) in a TPR-dependent manner . Ro 90-7501 has significant radiosensitizing effects on cervical cancer cells .
Assay Types