1. Anti-infection
  2. HCV
    Influenza Virus
  3. KIN1408

KIN1408 

Cat. No.: HY-19961 Purity: 99.55%
Handling Instructions

KIN1408 is an agonist of the RIG-1-like receptor (RLR) pathway and exhibits a broad-spectrum antiviral activity. KIN1408 exhibits activity against HCV, influenza A, dengue virus 2, Ebola, Nipah, and Lassa viruses.

For research use only. We do not sell to patients.

KIN1408 Chemical Structure

KIN1408 Chemical Structure

CAS No. : 1903800-11-2

Size Price Stock Quantity
1 mg USD 180 In-stock
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2520 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

KIN1408 is an agonist of the RIG-1-like receptor (RLR) pathway and exhibits a broad-spectrum antiviral activity. KIN1408 exhibits activity against HCV, influenza A, dengue virus 2, Ebola, Nipah, and Lassa viruses[1][2].

In Vitro

KIN1408 has the potency to drive IRF3 activation to induce innate immune gene (MDA5, RIG-1, Mx1, IRF7, and IFIT1 in THP-1 cells) expression and that concomitantly suppress dengue virus2 RNA to levels. KIN1408 also exhibits activity against HCV, influenza A, Ebola, Nipah, and Lassa viruses[1][2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

479.50

Formula

C₂₅H₁₉F₂N₃O₃S

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 39 mg/mL (81.33 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0855 mL 10.4275 mL 20.8551 mL
5 mM 0.4171 mL 2.0855 mL 4.1710 mL
10 mM 0.2086 mL 1.0428 mL 2.0855 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
KIN1408
Cat. No.:
HY-19961
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