2 Results for "

calphostin

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "calphostin" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-105416
CAS No.: 121263-19-2
Purity:  99.00%
Synonyms: UCN-1028C
Target:  

Antibiotic PKC Apoptosis

Research Areas:  

Metabolic Disease Cancer

Calphostin C is a highly selective PKC inhibitor (IC50=0.05 μM) and tumor apoptosis inducer. Calphostin C competitively binds to PKC and inhibits PKC-mediated phosphorylation signal transduction. Calphostin C restores Na+/K+ ATPase activity in the sciatic nerve of diabetic mice and improves neuropathy. Calphostin C can be used in the study of anti-tumor and diabetic complications .