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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
eEF1A
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "eEF1A" in MCE Product Catalog:
Forschungsgebiete:
Gamendazole, an indazole carboxylic acid (ICA), is an orally active, selective HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A) inhibitor. Gamendazole binds to the C-terminal nucleotide binding pocket of HSP90 and cause downregulation of clients AKT1 and ERBB2, but stabilizes the HSP90 heterocomplex. Gamendazole specifically inhibits the actin bundling function of EEF1A1, but does not bind to the nucleotide docking pocket nor inhibits the ribosome charging or protein translation functions of EEF1A1. Gamendazole, an antispermatogenic compound with antifertility effects, has the potential for reversible non-hormonal male contraceptive agent research [1] .
Art. -Nr.: HY-RS24785
Target:
Forschungsgebiete:
Eef1a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eef1a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS21848
Target:
Forschungsgebiete:
Eef1a2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eef1a2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS04174
Target:
Forschungsgebiete:
EEF1A1 Human Pre-designed siRNA Set A contains three designed siRNAs for EEF1A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS04175
Target:
Forschungsgebiete:
EEF1A2 Human Pre-designed siRNA Set A contains three designed siRNAs for EEF1A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-P72178
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCS 3; CCS3; Cervical cancer suppressor 3; chunp6927; CTCL tumor antigen; EE1A1; eEF 1; eEF1A; eEF1A-1; eEF1A1; EF-1-alpha-1; EF-Tu; EF1A; EF1A like protein; EF1A1_HUMAN; Elongation factor 1-alpha 1; Elongation factor Tu; GRAF 1EF; HNGC:16303; ik:tdsubc_2a3; ik:tdsubc_2b3; LENG7; member 7; PTI1; tdsubc_2a3; wu:fa91c07; wu:fa94b03; wu:fi13b09; xx:tdsubc_2a3; xx:tdsubc_2b3
Art. -Nr.: HY-179370
EEF1A2-IN-1 is a potent and covalen EEF1A2 inhibitor. EEF1A2-IN-1 exhibits selective antiproliferative activity against osteosarcoma (OS) cells. EEF1A2-IN-1 induces apoptosis by inhibiting EEF1A2 and downregulating the AKT signaling pathway. EEF1A2-IN-1 inhibits tumor growth in a xenograft mouse model. EEF1A2-IN-1 can be used for the research of OS [1].
Art. -Nr.: HY-RS18307
Target:
Forschungsgebiete:
Eef1a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eef1a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS28365
Target:
Forschungsgebiete:
Eef1a2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eef1a2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
