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Cat. No.: HY-N11500

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4,5-Dioxodehydroasimilobine

4,5-Dioxodehydroasimilobine is an alkaloid, which can be isolated from the genus Houttuynia.

For research use only. We do not sell to patients.

CAS No.: 82644-81-3
Formula: C₁₇H₁₁NO₄
Molecular Weight:293.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

4,5-Dioxodehydroasimilobine Chemical Structure

CAS No.: 82644-81-3

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

4,5-Dioxodehydroasimilobine is an alkaloid, which can be isolated from the genus Houttuynia^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
B-cell	IC₅₀	0.312 μM Compound: 14	Inhibition of LPS-induced BALB/c mouse B cell proliferation Inhibition of LPS-induced BALB/c mouse B cell proliferation	[PMID: 17081761]
RAW264.7	IC₅₀	>10 μM Compound: 5	Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced NO production pretreated for 30 mins followed by LPS stimulation for 24 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced NO production pretreated for 30 mins followed by LPS stimulation for 24 hrs by Griess assay	[PMID: 28499733]
T-cell	IC₅₀	4.93 μM Compound: 14	Inhibition of ConA-induced BALB/c mouse T cell proliferation Inhibition of ConA-induced BALB/c mouse T cell proliferation	[PMID: 17081761]

Chemical Information

CAS No. 82644-81-3
Molecular Weight 293.27
Formula C₁₇H₁₁NO₄
SMILES

O=C1NC2=CC3=C(C4=C2C(C1=O)=CC(O)=C4OC)C=CC=C3
Structure Classification
- Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wei Q U, et al. Alkaloids from Houttuynia cordata and their antiplatelet aggregation activities[J]. Chinese Journal of Natural Medicines, 2011, 9(6): 425-428.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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