2-Naphthylamine-6,8-disulfonic acid potassium 

2-Naphthylamine-6,8-disulfonic acid potassium is chemical that can be used for preparing dyestuff, medicine, agricultural chemicals etc^[1].

2-Naphthylamine-6,8-disulfonic acid potassium (Compound 20) can inhibit human immunodeficiency virus HIV-1 and HIV-2 by 11% and 13.6% at a concentration of 1369 μM, respectively^[1].
2-Naphthylamine-6,8-disulfonic acid potassium (ANDS) can directly analyze polyglycolic pyrophosphate-linked oligosaccharides in cell cultures and tissues^[3].
Guide (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). Labeling oligosaccharides^[3]:
1. Prepared 0.15 M ANDS with 15% (v/v) acetic acid.
2. Prepare 1M solution of sodium cyanoborohydride in dimethyl sulfoxide (DMSO).
3. Add 5 μL ANDS reagent (1 μL if sample is below 200 pM) to the sample.
4. Add 5 μL sodium cyanoborohydride solution (1 μL if sample is below 200 pM) to the sample.
5. After mixing, the reaction was briefly centrifuged and allowed to dry for 18 h at 37 °C.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

341.40

C₁₀H₈KNO₆S₂

842-15-9

O=S(C1=CC(S(=O)(O)=O)=C2C=C(N)C=CC2=C1)(O[K])=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. G T Tan, et al. Potential anti-AIDS naphthalenesulfonic acid derivatives. Synthesis and inhibition of HIV-1 induced cytopathogenesis and HIV-1 and HIV-2 reverse transcriptase activities. J Med Chem. 1992 Dec 25;35(26):4846-53.  [Content Brief]

  [2]. K B Lee, et al. A new method for sequencing linear oligosaccharides on gels using charged, fluorescent conjugates. Carbohydr Res. 1991 Jul 18;214(1):155-68.  [Content Brief]

  [3]. Ningguo Gao, et al. Fluorophore-assisted carbohydrate electrophoresis: a sensitive and accurate method for the direct analysis of dolichol pyrophosphate-linked oligosaccharides in cell cultures and tissues. Methods. 2005 Apr;35(4):323-7.  [Content Brief]

  [4]. Preparation method of 2-naphthylamine 6,8 disulfonic acid. CN102295585A.