2-Naphthylamine-6,8-disulfonic acid potassium

2-Naphthylamine-6,8-disulfonic acid potassium (Compound 20) can inhibit human immunodeficiency virus HIV-1 and HIV-2 by 11% and 13.6% at a concentration of 1369 μM, respectively^[1].
2-Naphthylamine-6,8-disulfonic acid potassium (ANDS) can directly analyze polyglycolic pyrophosphate-linked oligosaccharides in cell cultures and tissues^[3].
Guide (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). Labeling oligosaccharides^[3]:
1. Prepared 0.15 M ANDS with 15% (v/v) acetic acid.
2. Prepare 1M solution of sodium cyanoborohydride in dimethyl sulfoxide (DMSO).
3. Add 5 μL ANDS reagent (1 μL if sample is below 200 pM) to the sample.
4. Add 5 μL sodium cyanoborohydride solution (1 μL if sample is below 200 pM) to the sample.
5. After mixing, the reaction was briefly centrifuged and allowed to dry for 18 h at 37 °C.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.