1 Result for "

BAY 11-7082

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BAY 11-7082" in MCE Product Catalog:

488
488 Cited Publications
Cat. No.: HY-13453
CAS No.: 19542-67-7
Purity:  99.98%
Synonyms: BAY 11-7821
BAY 11-7082 is an IκBα phosphorylation and NF-κB inhibitor. BAY 11-7082 selectively and irreversibly inhibits the TNF-α-induced phosphorylation of IκB-α, and decreases NF-κB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 μM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells .
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