Map4k2 - mitogen activated protein kinase kinase kinase kinase 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 293694

About Map4k2

Primary_assembly 1: 203,645,153-203,660,331 forward strand.mRatBN7.2:CM026974.1

This gene has 1 transcript (splice variant), 101 orthologues, 36 paralogues and is associated with 5 phenotypes. Biased expression in Thymus (RPKM 158.7), Lung (RPKM 156.9) and 9 other tissues.

Summary

Predicted to enable ATP binding activity; MAP kinase kinase kinase kinase activity; and mitogen-activated protein kinase kinase kinase binding activity. Predicted to be involved in several processes, including positive regulation of MAPK cascade; protein phosphorylation; and vesicle targeting. Orthologous to human MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Map4k2 Products (1)

mRNA Protein Name
NM_001106329.1 NP_001099799.1 mitogen-activated protein kinase kinase kinase kinase 2

Map4k2 Protein Structure

STKc_MAP4K3_like

STKc_MAP4K3_like: cd06613 (15 - 271)

CNH

CNH: smart00036 (488 - 800)

  • 0
  • 200
  • 400
  • 600
  • 821 a.a.
Protein Preferred Names Protein Names

mitogen-activated protein kinase kinase kinase kinase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-15434 NG25 Inhibitor 98.68% Unkown
HY-148065 FMF-06-098-1 Inhibitor 98.77% Unkown
HY-77251 TAK1/MAP4K2 inhibitor 1 Inhibitor 99.91% Unkown
HY-123714 TL4-12 99.82% Unkown
HY-148061 DB1113 99.86% Unkown
HY-148063 DB0614 99.92% Unkown
HY-137343 DB-0646 Degrader 98.0% Unkown
HY-15434A NG25 trihydrochloride Inhibitor / Unkown
HY-RS08074 MAP4K2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08075 Map4k2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08076 Map4k2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map4k2 NCBI NCBI:5871