Eml4 - EMAP like 4 Gene
Species: Rattus norvegicus
Gene Type: protein coding
Gene ID: 313861
Summary
Predicted to enable alpha-tubulin binding activity; beta-tubulin binding activity; and microtubule binding activity. Predicted to be involved in attachment of spindle microtubules to kinetochore; microtubule Cytoskeleton organization; and mitotic metaphase plate congression. Predicted to act upstream of or within negative regulation of microtubule depolymerization. Predicted to be located in cytoplasm; microtubule cytoskeleton; and midbody. Predicted to colocalize with mitotic spindle. Orthologous to human EML4 (EMAP like 4). [provided by Alliance of Genome Resources, Apr 2022]
Eml4 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001108008.1 | NP_001101478.1 | echinoderm microtubule-associated protein-like 4 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
echinoderm microtubule-associated protein-like 4 |
|
Related Agents
- Approval
- Pre-clinical Phase
Approval
Bioactive Molecules
(2)
| Art. -Nr. | Produktname |
Wirkung
|
Reinheit |
Rare Diseases
|
|---|---|---|---|---|
| HY-12215 | Lorlatinib | 99.99% | Yes | |
| HY-12215R | Lorlatinib (Standard) | 99.92% | Unkown |
Pre-clinical Phase
Bioactive Molecules
(30)
| Art. -Nr. | Produktname |
Wirkung
|
Reinheit |
Rare Diseases
|
|---|---|---|---|---|
| HY-153386 | CPD-1224 | Inhibitor | 99.83% | Unkown |
| HY-112140 | JH-VIII-157-02 | Inhibitor | 98.98% | Unkown |
| HY-164397 | XMU-MP-5 | 99.00% | Unkown | |
| HY-111752 | EML4-ALK kinase inhibitor 1 | Inhibitor | 98.02% | Unkown |
| HY-170928 | DA-0157 | Inhibitor | 99.59% | Unkown |
| HY-135509 | Lorlatinib acetate | / | Unkown | |
| HY-105369 | KF-20444 | / | Unkown | |
| HY-131244 | ALK-IN-9 | Inhibitor | / | Unkown |
| HY-143557 | Trk-IN-7 | Inhibitor | / | Unkown |
| HY-155227 | ALK/EGFR-IN-1 | / | Unkown | |
| HY-155227A | ALK/EGFR-IN-2 | Inhibitor | / | Unkown |
| HY-155227B | ALK/EGFR-IN-3 | Inhibitor | / | Unkown |
| HY-161749 | PROTAC ALK degrader-1 | Degrader | / | Unkown |
| HY-161750 | PROTAC ALK degrader-2 | Degrader | / | Unkown |
| HY-161910 | SH-E4A-66 | Inhibitor | / | Unkown |
| HY-165284 | CM-118 | Inhibitor | / | Unkown |
| HY-170592 | dALK-3 | Degrader | / | Unkown |
| HY-174315 | WZH-17-002 | / | Unkown | |
| HY-174368 | PROTAC EML4-ALK Degrader-1 | / | Unkown | |
| HY-175527 | ALK degrader 2 | / | Unkown | |
| HY-175849 | ALK degrader 1 | / | Unkown | |
| HY-180956 | PROTAC ALK degrader-5 | / | Unkown | |
| HY-180964 | Lys-PEG3-BA | Degrader | / | Unkown |
| HY-180965 | Pro-PEG3-BA | / | Unkown | |
| HY-180966 | Gly-PEG3-BA | Degrader | / | Unkown |
| HY-180970 | TD-004 | Degrader | / | Unkown |
| HY-180972 | PROTAC EML4-ALK Degrader-2 | Inhibitor | / | Unkown |
| HY-E70713 | EML4 ALK Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70714 | EML4 ALK F1174L Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-RS04356 | EML4 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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