IDO1-IN-13
IDO1-IN-13 (compound 27a) is a potent IDO1 inhibitor with an IC50 of 61.6 nM. IDO1-IN-13 has cellular IDO1 inhibition (HeLa EC50= 30 nM). IDO1-IN-13 decreases 51% of the kyn/trp ratio in SK-OV-3 xenograft tumor tissues.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C20H16BrN5O2S
- Molecular Weight:470.34
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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IDO1 30 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Detroit 551 | CC50 |
>10 μM
Compound: 27a
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Cytotoxicity against human Detroit 551 cells assessed as reduction in cell viability after 72 hrs by MTS assay
Cytotoxicity against human Detroit 551 cells assessed as reduction in cell viability after 72 hrs by MTS assay
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[PMID: 34929581] |
Chemical Information
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Molecular Weight 470.34
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Formel C20H16BrN5O2S
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SMILES
N#CC1=CC=C(C=C1)NC(NCC2=CSC(/C(NC3=CC=CC(Br)=C3)=N/O)=C2)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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