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Cat. No.: HY-162592

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EYA2-IN-1

EYA2-IN-1(compound 2e) is a novel allosteric EYA2 inhibitor. EYA2-IN-1 has anti-tumor activity.

For research use only. We do not sell to patients.

Formula: C₁₇H₁₂FN₃OS₂
Molecular Weight:357.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

EYA2-IN-1 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

EYA2-IN-1(compound 2e) is a novel allosteric EYA2 inhibitor. EYA2-IN-1 has anti-tumor activity^[1].

Chemical Information

Molecular Weight 357.43
Formula C₁₇H₁₂FN₃OS₂
SMILES

O=C(C1=CC=CC(F)=C1)N/N=C/C2=CC=C(S2)SC3=NC=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lukas Gardner, et al. Rational design of novel allosteric EYA2 inhibitors as potential therapeutics for multiple brain cancers. ChemMedChem. 2024 Jun 11:e202400179. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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