α-Synuclein 4554W
Based on 1 Customer Validation
α-Synuclein 4554W is an inhibitor of α-Synuclein (aSyn) aggregation with associated toxicity. α-Synuclein 4554W consists of GIVNGVKA sequences, previously identified through intracellular library screening. α-Synuclein 4554W reduces fibril formation of aSyn mutants assocaited with Parkinson’s disease.
For research use only. We do not sell to patients.
- Purity: 99.53%
- CAS No.: 2243207-00-1
- Formula: C45H80N14O14
- Molecular Weight:1041.20
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Peptide Compound Library
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Bioactive Compound Library
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High-Throughput Bioactive Compound Library
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All α-synuclein Isoforms
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Biological Activity
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α-synuclein Aggregation |
Chemical Information
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CAS No. 2243207-00-1
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Appearance Solid
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Molecular Weight 1041.20
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Formula C45H80N14O14
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Color White to off-white
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Sequence
Ac-Lys-Asp-Gly-Ile-Val-Asn-Gly-Val-Lys-Ala-NH2
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Sequence Shortening
Ac-KDGIVNGVKA-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 50 mg/mL (48.02 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.9604 mL | 4.8022 mL | 9.6043 mL | 24.0108 mL |
| 5 mM | 0.1921 mL | 0.9604 mL | 1.9209 mL | 4.8022 mL | |
| 10 mM | 0.0960 mL | 0.4802 mL | 0.9604 mL | 2.4011 mL | |
| 15 mM | 0.0640 mL | 0.3201 mL | 0.6403 mL | 1.6007 mL | |
| 20 mM | 0.0480 mL | 0.2401 mL | 0.4802 mL | 1.2005 mL | |
| 25 mM | 0.0384 mL | 0.1921 mL | 0.3842 mL | 0.9604 mL | |
| 30 mM | 0.0320 mL | 0.1601 mL | 0.3201 mL | 0.8004 mL | |
| 40 mM | 0.0240 mL | 0.1201 mL | 0.2401 mL | 0.6003 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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