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Cat. No.: HY-185347

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AChE-IN-114

AChE-IN-114 is a selective AChE inhibitor and shows weak inhibitory activity for BChE. AChE-IN-114 can be used for the research of alzheimer’s disease.

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CAS No.: 2365405-51-0
Formule: C₁₈H₁₂Cl₂O₃
Masse moléculaire:347.19

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AChE-IN-114 Chemical Structure

CAS No.: 2365405-51-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
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Activité biologique

Description

AChE-IN-114 is a selective AChE inhibitor and shows weak inhibitory activity for BChE. AChE-IN-114 can be used for the research of alzheimer’s disease^[1].

IC₅₀ & Target^[1]

AChE

BChE

Voir tous les produits spécifiques à Isoform Cholinesterase (ChE) :

AChE
BChE

In Vitro

AChE-IN-114 (Compound 2v) (10 μM) acts as a mixed type inhibitor of electric eel acetylcholinesterase with a K_i of 12.19-21.46 μM, shows minimal butyrylcholinesterase inhibition, and is non-cytotoxic to multiple human tumor and non-malignant mouse fibroblast cell lines with an EC₅₀ >30 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2365405-51-0
Masse moléculaire 347.19
Formule C₁₈H₁₂Cl₂O₃
SMILES

O=C(OC(/C=C/C1=CC=CC=C1Cl)=O)/C=C/C2=CC=CC(Cl)=C2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Gießel JM, et al. Substituted cinnamic anhydrides act as selective inhibitors of acetylcholinesterase. Bioorg Chem. 2019;90:103058. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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AChE-IN-114

Voir tous les produits spécifiques à Isoform Cholinesterase (ChE)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

AChE-IN-114 Related Classifications

HY-185347 Related Classifications