74848-84-3
74848-84-3
Chemical Structure
Thymidine-d3
Synonym(s): DThyd-d3;NSC 21548-d3
- CAS No.: 74848-84-3
- Formula:C10H11D3N2O5
- Molecular Weight:245.25
IUPAC Name: 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(methyl-d3)pyrimidine-2,4(1H,3H)-dione
InChIKey: IQFYYKKMVGJFEH-BXKFBODDSA-N
SMILES: O=C1N(C=C(C(N1)=O)C([2H])([2H])[2H])[C@]2([H])O[C@@H]([C@H](C2)O)CO
Biological Activity: Thymidine-d3 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1][2][3].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Thymidine-d3 | 99.8% | Thymidine-d3 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine (Standard) | 99.98% | Thymidine (Standard) is the analytical standard of Thymidine. This product is intended for research and analytical applications. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine-13C-2 | Thymidine-13C-2 is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine-13C10 | 95.0% | Thymidine-13C10 (DThyd-13C10; NSC 21548-13C10) is 13C-labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine-2′-13C | 98.12% | Thymidine-2′-13C is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine-13C | 99.11% | Thymidine-13C is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine-d4 | 99.99% | Thymidine-d4 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine-113C,15N2 | Thymidine-13C,15N2 is the 13C- and 15N-labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine-13C10,15N2 | 99.97% | Thymidine-13C10,15N2 is the 13C and 15N labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine-d2 | Thymidine-d2 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1 | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine-13C5 | 99.90% | Thymidine-13C5 (DThyd-13C5; NSC 21548-13C5) is 13C-labeled Thymidine (HY-N1150). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine-13C-1 | Thymidine-13C-1 is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine-d14 | Thymidine-d14 (DThyd-d14; NSC 21548-d14) is deuterium labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine-15N2 | 99.0% | Thymidine-15N2 is the 15N labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Thymidine | 99.94% | Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8(17). [Content Brief]
- [3]. FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4604):274-5.FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4604):274-5. [Content Brief]
