D-Alanine-13C3
D-Alanine-13C3 ((R)-Alanine-13C3) is the 13C-labeled D-Alanine (HY-41700). D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
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- CAS No.: 286460-72-8
- Formule: 13C3H7NO2
- Masse moléculaire:92.07
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 286460-72-8
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Unlabeled Cas 338-69-2
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Masse moléculaire 92.07
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Formule 13C3H7NO2
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SMILES
N[13C@H]([13CH3])[13C](O)=O
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Synonyms
(R)-Alanine-13C3; Ba 2776-13C3; D-α-Alanine-13C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Schmieden V, et al. Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol Pharmacol. 1995 Nov;48(5):919-27. [Content Brief]
[2]. Saitoh T, et al. A novel antagonist, phenylbenzene omega-phosphono-alpha-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br J Pharmacol. 1994 Sep;113(1):165-70. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)