Hyptadienic acid
Based on 1 Customer Validation
Hyptadienic acid is a triterpene acid that can be isolated from the leaves of Perilla frutescens. Hyptadienic acid inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice with an ID50 value of 0.13 mg/ear. Hyptadienic acid can be used for the research of inflammation.
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- Pureté: 93.0%
- CAS No.: 128397-09-1
- Formule: C30H46O4
- Masse moléculaire:470.68
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Stockage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Activité biologique
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
24.68 μM
Compound: 32
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 20515057] |
| A549 | IC50 |
7.4 μM
Compound: 37
|
Anticancer activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Anticancer activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37146221] |
| HL-60 | IC50 |
15.48 μM
Compound: 32
|
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 20515057] |
| MCF7 | IC50 |
>10 μM
Compound: 37
|
Anticancer activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Anticancer activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37146221] |
| MCF7 | IC50 |
>40 μM
Compound: 32
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 20515057] |
| MDA-MB-231 | IC50 |
>10 μM
Compound: 37
|
Anticancer activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Anticancer activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37146221] |
| NCI-H1975 | IC50 |
>10 μM
Compound: 37
|
Anticancer activity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Anticancer activity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 37146221] |
| SMMC-7721 | IC50 |
21.01 μM
Compound: 32
|
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
|
[PMID: 20515057] |
| SW480 | IC50 |
10.86 μM
Compound: 32
|
Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
|
[PMID: 20515057] |
Chemical Information
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CAS No. 128397-09-1
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Appearance Solid
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Masse moléculaire 470.68
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Formule C30H46O4
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Color White to off-white
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SMILES
C[C@@]12C([C@@]3([H])[C@](C(O)=O)(CC[C@@H](C)[C@]3(O)C)CC2)=CC[C@@]4([H])[C@]1(CC[C@]5([H])[C@@]4(C(CO)=CC5(C)C)C)C
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)