LEB-03-144
LEB-03-144 is a WEE1 DUBTAC (deubiquitinase-targeting chimera) linking AZD1775 (Adavosertib) to the OTUB1 recruiter EN523 through a C3 alkyl linker. LEB-03-144 shows significant WEE1 stabilization in HEP3B hepatoma cancer cells.
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- CAS No.: 2858812-89-0
- Formule: C43H51N11O6
- Masse moléculaire:817.94
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Chemical Information
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CAS No. 2858812-89-0
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Masse moléculaire 817.94
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Formule C43H51N11O6
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SMILES
C=CCN1C(C2=C(N1C3=NC(C(C)(O)C)=CC=C3)N=C(N=C2)NC4=CC=C(C=C4)N5CCN(CC5)CCCNC(CCC6=CC=C(O6)N7CCN(CC7=O)C(C=C)=O)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LEB-03-144 Related Classifications
HY-143342 Related Classifications
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