9 Results for "

RadD

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "RadD" in MCE Product Catalog:

7
Peiminine
Peiminine
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7 Cited Publications
Cat. No.: HY-N0213
CAS No.: 18059-10-4
Synonyms: Verticinone; RadDeanine
Category:  

Alkaloids Piperidine Alkaloids Liliaceae Fritillaria thunbergii Miq. Plants Disease Research Fields Cancer

Target:  

Autophagy Caspase Bcl-2 Family PARP p38 MAPK ERK NF-κB Apoptosis

Peiminine is a compound that can be isolated from Bolbostemma paniculatum (Maxim) Franquet (Cucurbitaceae family). Peiminine can induce apoptosis in human hepatocellular carcinoma HepG2 cells through both extrinsic and intrinsic apoptotic pathways. Peiminine has anti-inflammatory, anticancer, anti-osteoporosis, cardioprotective and other activities in many animal models .
1
Raddeanin A
Raddeanin A
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1 Cited Publications
Cat. No.: HY-N0819
CAS No.: 89412-79-3
Category:  

Triterpenes other families Terpenoids Plants Disease Research Fields Cancer

Target:  

Apoptosis PI3K Akt ERK mTOR Wnt β-catenin Wee1 JNK VEGFR CDK

Raddeanin A is an oleanane-type triterpenoid saponin with oral activity. Raddeanin A inhibits SRC, mTOR, JNK, VEGFR2, NLRP3 inflammasome, Wnt/β-catenin, Wee1, PI3K/AKT signaling pathway, MAPK/ERK signaling pathway, AR-FL, AR-Vs, and downregulates the expression of p-PI3K and p-AKT. Raddeanin A inhibits osteoclast formation, bone resorption, osteolysis, cancer cell invasion, migration, proliferation, angiogenesis and epithelial-mesenchymal transition, while induces apoptosis, cell cycle arrest, ROS production, immunogenic cell death and dendritic cell maturation. Raddeanin A improves blood-retinal barrier function, alleviates inflammation, regulates the tumor microenvironment, and enhances the activity of anti-PD-1 antibody. Raddeanin A is applicable to the research of breast cancer-associated osteolysis, human osteosarcoma, colorectal cancer, glioblastoma, Alzheimer's disease, cholangiocarcinoma, melanoma, non-small cell lung cancer, castration-resistant prostate cancer and multiple myeloma .
Raddeanoside R8
Raddeanoside R8
0 Images
Cat. No.: HY-107242
CAS No.: 124961-61-1
Pureté:  99.76%
Category:  

Triterpenes Anemone cathayensis Kitag. Terpenoids Ranunculaceae Anemone raddeana Regel Other Diseases Plants Disease Research Fields

Target:  

Others

Raddeanoside R8 is a saponin that can be isolated from fresh rhizoma of Anemone raddeana Regel .
Raddeanoside 20
Raddeanoside 20
0 Images
Cat. No.: HY-N4174
CAS No.: 335354-79-5
Category:  

Triterpenes Terpenoids Ranunculaceae Anemone raddeana Regel Metabolic Disease Plants Disease Research Fields

Target:  

Reactive Oxygen Species (ROS)

Raddeanoside 20 is a triterpenoid isolated from the rhizome of Anemone raddeana. Raddeanoside 20 can suppresse superoxide generation .
Raddeanin A (Standard)
Raddeanin A (Standard)
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Cat. No.: HY-N0819R
CAS No.: 89412-79-3
Category:  

Triterpenes other families Terpenoids Plants

Target:  

Reference Standards Apoptosis PI3K Akt ERK mTOR Wnt β-catenin Wee1 JNK VEGFR CDK

Raddeanin A (Standard) is the analytical standard of Raddeanin A (HY-N0819). This product is intended for research and analytical applications. Raddeanin A is an oleanane-type triterpenoid saponin with oral activity. Raddeanin A inhibits SRC, mTOR, JNK, VEGFR2, NLRP3 inflammasome, Wnt/β-catenin, Wee1, PI3K/AKT signaling pathway, MAPK/ERK signaling pathway, AR-FL, AR-Vs, and downregulates the expression of p-PI3K and p-AKT. Raddeanin A inhibits osteoclast formation, bone resorption, osteolysis, cancer cell invasion, migration, proliferation, angiogenesis and epithelial-mesenchymal transition, while induces apoptosis, cell cycle arrest, ROS production, immunogenic cell death and dendritic cell maturation. Raddeanin A improves blood-retinal barrier function, alleviates inflammation, regulates the tumor microenvironment, and enhances the activity of anti-PD-1 antibody. Raddeanin A is applicable to the research of breast cancer-associated osteolysis, human osteosarcoma, colorectal cancer, glioblastoma, Alzheimer's disease, cholangiocarcinoma, melanoma, non-small cell lung cancer, castration-resistant prostate cancer and multiple myeloma.
Raddeanoside R17
Raddeanoside R17
0 Images
Cat. No.: HY-N8096
CAS No.: 824401-07-2
Synonyms: Pulchinenoside E3
Category:  

Triterpenes Terpenoids Ranunculaceae Plants Disease Research Fields Inflammation/Immunology Pulsatilla cernua (Thunb.) Bercht. et Opiz.

Target:  

Others

Raddeanoside R17 (Pulchinenoside E3) is a saponin compound that can be isolated from the root of Pulsatilla koreana. Raddeanoside R17 shows anti-inflammatory effects .
Peiminine (Standard)
Peiminine (Standard)
0 Images
Cat. No.: HY-N0213R
CAS No.: 18059-10-4
Synonyms: Verticinone (Standard); RadDeanine (Standard)
Category:  

Alkaloids Piperidine Alkaloids Liliaceae Fritillaria thunbergii Miq. Plants

Target:  

Reference Standards Autophagy Caspase Bcl-2 Family PARP p38 MAPK ERK NF-κB Apoptosis

Peiminine (Standard) is the analytical standard of Peiminine. This product is intended for research and analytical applications. Peiminine is a compound that can be isolated from Bolbostemma paniculatum (Maxim) Franquet (Cucurbitaceae family). Peiminine can induce apoptosis in human hepatocellular carcinoma HepG2 cells through both extrinsic and intrinsic apoptotic pathways. Peiminine has anti-inflammatory, anticancer, anti-osteoporosis, cardioprotective and other activities in many animal models .
Raddeanoside R16
Raddeanoside R16
0 Images
Cat. No.: HY-N11458
CAS No.: 824401-05-0
Category:  

Triterpenes Terpenoids Ranunculaceae Anemone raddeana Regel Plants Pentacyclic Triterpenoids

Target:  

Others

Raddeanoside R16 is an oleanane-type saponin, that can be isolated from the rhizoma of Anemone raddeana .
Raddeanoside R22
Raddeanoside R22
0 Images
Cat. No.: HY-N19898
CAS No.: 1215281-16-5
Category:  

Triterpenes Terpenoids Ranunculaceae Anemone raddeana Regel Plants

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