23 Results for "

BCAAs

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "BCAAs" in MCE Product Catalog:

16
L-Leucine
L-Leucine
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16 Publications Verification
Art. -Nr.: HY-N0486
CAS. Nr.: 61-90-5
Synonyms: Leucine
Category:  

Metabolic Disease Amino acids Endogenous metabolite

Target:  

mTOR Endogenous Metabolite Ligands for E3 Ligase

L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
3
L-Leucine-d3
L-Leucine-d3
0 Images
3 Cited Publications
Art. -Nr.: HY-N0486S9
CAS. Nr.: 87828-86-2
L-Leucine-d3 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
1
L-Leucine (Standard)
L-Leucine (Standard)
0 Images
1 Cited Publications
Art. -Nr.: HY-N0486R
CAS. Nr.: 61-90-5
Synonyms: Leucine (Standard)
Category:  

Zea mays L. Endocrine diseases Amino acids Plants Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Gramineae Disease markers Nervous System Disorder Cardiovascular System Disorder

Target:  

Reference Standards mTOR Endogenous Metabolite

L-Leucine (Standard) is the analytical standard of L-Leucine. This product is intended for research and analytical applications. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
1
L-Leucine-d10
L-Leucine-d10
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1 Cited Publications
Art. -Nr.: HY-N0486S
CAS. Nr.: 106972-44-5
L-Leucine-d10 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
1
L-Leucine-13C6,15N
L-Leucine-13C6,15N
0 Images
1 Cited Publications
Art. -Nr.: HY-N0486S8
CAS. Nr.: 202406-52-8
L-Leucine- 13C6, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
L-Leucine-13C
L-Leucine-13C
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Art. -Nr.: HY-N0486S1
CAS. Nr.: 74292-94-7
L-Leucine- 13C is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
PF-07328948
PF-07328948
0 Images
Art. -Nr.: HY-159648
CAS. Nr.: 2936625-34-0
Target:  

Endogenous Metabolite

Forschungsgebiete:  

Cardiovascular Disease

PF-07328948 is an orally effective BDK (branch chain ketoacid dehydrogenase kinase) inhibitor, with IC50 of 110 nM. PF-07328948 acts as a BCKDH (branch chain ketoacid dehydrogenase) enzyme complex degrader to enhance BCAA (branch chain amino acid) catabolism. PF-07328948 improves metabolic and heart failure end points in rats .
Nicosulfuron
Nicosulfuron
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Art. -Nr.: HY-B1876
CAS. Nr.: 111991-09-4
Target:  

Environmental Pollutants Acetolactate Synthase (ALS)

Forschungsgebiete:  

Others

Nicosulfuron is efficient, harmless, antifungal and selective herbicide belonging to the sulfonylurea family. Nicosulfuron is also a photosynthetic system inhibitor and inhibits acetolactate synthase (ALS) enzyme activity. Nicosulfuron degradation by Plectosphaerella cucumerina AR1 is glucose concentration dependent in planktonic lifestyle. Nicosulfuron enhances the glycolysis pathway and tricarboxylic acid cycle to improve the adaptability of sweet maize. Nicosulfuron reduces the synthesis of branched-chain amino acids (BCAAs), which is proming for maize cultivation .
L-Leucine-13C6
L-Leucine-13C6
0 Images
Art. -Nr.: HY-N0486S2
CAS. Nr.: 201740-84-3
Leucine- 13C6 is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
LAGIPRA peptide TFA
LAGIPRA peptide TFA
0 Images
Art. -Nr.: HY-P11285A
Synonyms: Long acting GIPRA-1 TFA
Target:  

Insulin Receptor

Forschungsgebiete:  

Metabolic Disease

LAGIPRA peptide TFA is a long-acting GIP1R agonist. LAGIPRA peptide TFA enhances insulin sensitivity by augmenting glucose disposal and reduces branched-chain amino acids (BCAAs) and ketoacids. LAGIPRA peptide TFA has the potential for the research of type 2 diabetes .
L-Leucine-2-13C,15N
L-Leucine-2-13C,15N
0 Images
Art. -Nr.: HY-N0486S6
CAS. Nr.: 285977-88-0
L-Leucine-2- 13C, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
PF-07247685
PF-07247685
0 Images
Art. -Nr.: HY-155157
Reinheit:  98.66%
Category:  

Cardiovascular Disease Natural Products Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

PF-07247685 is a BCKDC kinase (BDK) inhibitor (EC50=2.2 nM). PF-07247685 stabilizes the interaction between BDK and BCKDH core subunit E2 and prevents phosphorylation of E1. While BDK mediates branched-chain ketoacid dehydrogenase (BCKDH) phosphorylation, and inhibition of BCKDH is involved in controlling the rate-limiting step of branched-chain amino acid (BCAA) degradation. Impaired BCAA catabolism has been associated with several diseases, particularly cardiometabolic diseases, including heart failure (HF), type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver disease (NAFLD), and obesity. PF-07247685 improved cardiometabolic endpoints and improves glucose tolerance in mice .
PF-07208254
PF-07208254
0 Images
Art. -Nr.: HY-156193
CAS. Nr.: 2573122-40-2
Reinheit:  99.69%
Category:  

Cardiovascular Disease Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields

Target:  

PDHK

PF-07208254 is a selective, orally active allosteric inhibitor of branched-chain ketoacid dehydrogenase kinase (BDK) (IC50=110 nM, Ki=54 nM, KD=84 nM). PF-07208254 inhibits BDK-mediated BCKDH phosphorylation and enhances the catabolism of branched-chain amino acids (BCAAs) and branched-chain keto acids (BCKAs) by binding to the allosteric pocket of BDK, reducing BDK binding to BCKDH-E2 and promoting BDK degradation. PF-07208254 inhibits BDK activity in human skeletal muscle cells (IC50=540 nM) and has activity to improve cardiac function and metabolism. PF-07208254 can be used in the study of cardiometabolic diseases (e.g., heart failure, type 2 diabetes) .
L-Leucine-d7
L-Leucine-d7
0 Images
Art. -Nr.: HY-N0486S4
CAS. Nr.: 92751-17-2
L-Leucine-d7 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
L-Leucine-15N
L-Leucine-15N
0 Images
Art. -Nr.: HY-N0486S3
CAS. Nr.: 59935-31-8
L-Leucine- 15N is the 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
LAGIPRA peptide
LAGIPRA peptide
0 Images
Art. -Nr.: HY-P11285
Synonyms: Long acting GIPRA-1
Target:  

Insulin Receptor

Forschungsgebiete:  

Metabolic Disease

LAGIPRA peptide is a long-acting GIP1R agonist. LAGIPRA peptide enhances insulin sensitivity by augmenting glucose disposal and reduces branched-chain amino acids (BCAAs) and ketoacids. LAGIPRA peptide has the potential for the research of type 2 diabetes .
L-Leucine-d2
L-Leucine-d2
0 Images
Art. -Nr.: HY-N0486S12
CAS. Nr.: 362049-59-0
L-Leucine-d2 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
L-Leucine-18O2
L-Leucine-18O2
0 Images
Art. -Nr.: HY-N0486S10
CAS. Nr.: 73579-45-0
L-Leucine- 18O2 is the 18O-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
L-Leucine-d1
L-Leucine-d1
0 Images
Art. -Nr.: HY-N0486S11
CAS. Nr.: 89836-93-1
L-Leucine-d is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
L-Leucine-2-13C
L-Leucine-2-13C
0 Images
Art. -Nr.: HY-N0486S5
CAS. Nr.: 201612-66-0
L-Leucine-2- 13C is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
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