2936625-34-0

PF-07328948 Chemical Structure
2936625-34-0

Chemical Structure

PF-07328948

  • CAS No.: 2936625-34-0
  • Formula:C16H8F4O3S
  • Molecular Weight:356.29

InChIKey: FXLDAQFHCAENIV-UHFFFAOYSA-N

SMILES: FC1=C(C=C(C(F)=C1OC)C2=C(C(O)=O)SC3=CC(F)=CC=C23)F

Biological Activity: PF-07328948 is an orally effective BDK (branch chain ketoacid dehydrogenase kinase) inhibitor, with IC50 of 110 nM. PF-07328948 acts as a BCKDH (branch chain ketoacid dehydrogenase) enzyme complex degrader to enhance BCAA (branch chain amino acid) catabolism. PF-07328948 improves metabolic and heart failure end points in rats[1].

Cat. No. Product Name Purity Description Pricing
HY-159648 		PF-07328948 99.88% PF-07328948 is an orally effective BDK (branch chain ketoacid dehydrogenase kinase) inhibitor, with IC50 of 110 nM. PF-07328948 acts as a BCKDH (branch chain ketoacid dehydrogenase) enzyme complex degrader to enhance BCAA (branch chain amino acid) catabolism. PF-07328948 improves metabolic and heart failure end points in rats.
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