29-Nor-20-oxolupeol
29-Nor-20-oxolupeol, extracted from Impatiens basamina, reduces NO levels in LPS-activated murine microglial cells with an IC50 of 44.21 µM.
For research use only. We do not sell to patients.
- Purity: 99.84%
- CAS No.: 19891-85-1
- Formula: C29H48O2
- Molecular Weight:428.69
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
>10 μM
Compound: 25
|
Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
|
[PMID: 24467317] |
| A549 | IC50 |
>10 μM
Compound: 25
|
Cytotoxicity against human A549 cells after 96 hrs by MTT assay
Cytotoxicity against human A549 cells after 96 hrs by MTT assay
|
[PMID: 24467317] |
| Bel-7402 | IC50 |
>10 μM
Compound: 25
|
Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay
Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay
|
[PMID: 24467317] |
| BGC-823 | IC50 |
>10 μM
Compound: 25
|
Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay
Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay
|
[PMID: 24467317] |
| BV-2 | IC50 |
6.09 μM
Compound: 25
|
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method
|
[PMID: 24467317] |
| HCT-8 | IC50 |
>10 μM
Compound: 25
|
Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
|
[PMID: 24467317] |
Chemical Information
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CAS No. 19891-85-1
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Appearance Solid
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Molecular Weight 428.69
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Formula C29H48O2
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Color White to off-white
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SMILES
C[C@@]([C@@]1(CC[C@@]2([H])C3(C)C)C)(CC4)[C@@](CC[C@]1([H])[C@]2(CC[C@@H]3O)C)([H])[C@]([C@@H]5C(C)=O)([H])[C@@]4(CC5)C
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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