Aβ42 agonist-2
Based on 1 Customer Validation
Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells.
For research use only. We do not sell to patients.
- Purity: 99.92%
- CAS No.: 6314-40-5
- Formula: C15H11NOS
- Molecular Weight:253.32
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Aβ42 aggregation[1]
Chemical Information
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CAS No. 6314-40-5
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Appearance Solid
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Molecular Weight 253.32
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Formula C15H11NOS
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SMILES
O=C(C1=CC2=C(C=CC=C2)S1)NC3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 125 mg/mL (493.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9476 mL | 19.7379 mL | 39.4758 mL | 98.6894 mL |
| 5 mM | 0.7895 mL | 3.9476 mL | 7.8952 mL | 19.7379 mL | |
| 10 mM | 0.3948 mL | 1.9738 mL | 3.9476 mL | 9.8689 mL | |
| 15 mM | 0.2632 mL | 1.3159 mL | 2.6317 mL | 6.5793 mL | |
| 20 mM | 0.1974 mL | 0.9869 mL | 1.9738 mL | 4.9345 mL | |
| 25 mM | 0.1579 mL | 0.7895 mL | 1.5790 mL | 3.9476 mL | |
| 30 mM | 0.1316 mL | 0.6579 mL | 1.3159 mL | 3.2896 mL | |
| 40 mM | 0.0987 mL | 0.4934 mL | 0.9869 mL | 2.4672 mL | |
| 50 mM | 0.0790 mL | 0.3948 mL | 0.7895 mL | 1.9738 mL | |
| 60 mM | 0.0658 mL | 0.3290 mL | 0.6579 mL | 1.6448 mL | |
| 80 mM | 0.0493 mL | 0.2467 mL | 0.4934 mL | 1.2336 mL | |
| 100 mM | 0.0395 mL | 0.1974 mL | 0.3948 mL | 0.9869 mL |
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