6314-40-5
Chemical Structure
Aβ42 agonist-2
- CAS No.: 6314-40-5
- Formula:C15H11NOS
- Molecular Weight:253.32
InChIKey: QFWHYKVMOFOKHM-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(C=CC=C2)S1)NC3=CC=CC=C3
Biological Activity: Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells[1].
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Aβ42 agonist-2 | 99.92% | Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells. | ||||||||||||||||||||
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Keywords