Antibacterial agent 329
Antibacterial agent 329 (Compound 9c) is an antibacterial agent. Antibacterial agent 329 inhibits the activity of MraY. Antibacterial agent 329 exhibits antibacterial activity against Escherichia coli K12 and Bacillus subtilis W23 with a MIC of 16 μg/mL, but shows no activity against Pseudomonas fluorescens Pf-5. Antibacterial agent 329 exerts antibacterial activity against Acinetobacter baumannii 19606, Staphylococcus aureus MRSA USA300 JE2, Enterobacter cloacae 19434, Klebsiella pneumoniae 700603 and Enterococcus faecium 19434, with MIC values of 8, 8, 16-32, 16-32 and 16 μg/mL, respectively, while it shows no activity against Pseudomonas aeruginosa NCTC 13437.
For research use only. We do not sell to patients.
- Formula: C17H14F3N3O
- Molecular Weight:333.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Antibacterial agent 329 exhibits antimicrobial activity against Escherichia coli K12 and Bacillus subtilis W23 with an MIC of 16 μg/mL, and no activity against Pseudomonas fluorescens Pf-5[1].
Antibacterial agent 329 exhibits antimicrobial activity against Acinetobacter baumannii 19606, Staphylococcus aureus MRSA USA300 JE2, Enterobacter cloacae 19434, Klebsiella pneumoniae 700603, and Enterococcus faecium 19434 with MIC values of 8, 8, 16-32, 16-32, and 16 μg/mL respectively, and no activity against Pseudomonas aeruginosa NCTC 13437[1].
Antibacterial agent 329 (200 μM) inhibits particulate Escherichia coli MraY activity by 33%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 333.31
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Formula C17H14F3N3O
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SMILES
NC1=NC=C(N1)C2=CC=CC=C2OCC3=CC=C(C(F)(F)F)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Antibacterial agent 329
- Antibacterial agent329
- Antibacterial agent-329
- Bacterial
- Bacillus subtilis W23
- Escherichia coli translocase MraY
- peptidoglycan biosynthesis pathway
- Escherichia coli K12
- Staphylococcus aureus MRSA USA300
- acinetobacter baumannii infection
- staphylococcus aureus mrsa infection
- Acinetobacter baumannii 19606
- HepG2 cells
- Pseudomonas fluorescens Pf-5
- Inhibitor
- inhibitor
- inhibit